Thimerosal
CAS No. 54-64-8
Thimerosal ( Thiomersalate;Mercurothiolate )
产品货号. M19490 CAS No. 54-64-8
Thimerosal is an organomercurial compound and derivative of thiosalicyclic acid with antibacterial and antifungal properties.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
100MG | 获取报价 | 有现货 |
|
200MG | 获取报价 | 有现货 |
|
500MG | 获取报价 | 有现货 |
|
1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称Thimerosal
-
注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
-
产品简述Thimerosal is an organomercurial compound and derivative of thiosalicyclic acid with antibacterial and antifungal properties.
-
产品描述Thimerosal is an organomercurial compound and derivative of thiosalicyclic acid with antibacterial and antifungal properties. Although the mechanism of action has not been fully elucidated thimerosal inhibits sulfhydryl-containing active site of various enzymes and binds to sulfhydryl compounds such as glutathione cysteine and SH groups of proteins. In addition thimerosal activates the InsP3 calcium channel on endoplasmic reticular membrane thereby triggering the release of calcium from intracellular stores resulting in a calcium-induced calcium-influx of extracellular calcium. Consequently thimerosal may induce or inhibit cellular functions dependent on calcium signaling.
-
同义词Thiomersalate;Mercurothiolate
-
通路GPCR/G Protein
-
靶点Antibacterial
-
受体Antibacterial
-
研究领域Inflammation/Immunology
-
适应症Septic; Fungal Infection
化学信息
-
CAS Number54-64-8
-
分子量404.81
-
分子式C9H9HgNaO2S
-
纯度>98% (HPLC)
-
溶解度DMSO:10 mM
-
SMILES[Na+].CC[Hg]SC1=CC=CC=C1C([O-])=O
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1.Li X et al. Toxicol Sci. 2014 Jun;139(2):452-65.
产品手册
关联产品
-
GSK693
GSK693 (GSK-693) is a potent, direct inhibitor of M. tuberculosis enoyl-ACP reductase (InhA) with IC50 of 7 nM.
-
Gentamycin sulfate
Gentamycin Sulfate is a broad-spectrum, aminoglycoside antibiotic used for cell culture which inhibits protein synthesis in sensitive organisms.
-
Qstatin
QStatin a Selective Inhibitor of Quorum Sensing in?Vibrio?Species( SmcR with an EC50 of 208.9 nM).