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Thimerosal

CAS No. 54-64-8

Thimerosal ( Thiomersalate;Mercurothiolate )

产品货号. M19490 CAS No. 54-64-8

Thimerosal is an organomercurial compound and derivative of thiosalicyclic acid with antibacterial and antifungal properties.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
100MG 获取报价 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Thimerosal
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Thimerosal is an organomercurial compound and derivative of thiosalicyclic acid with antibacterial and antifungal properties.
  • 产品描述
    Thimerosal is an organomercurial compound and derivative of thiosalicyclic acid with antibacterial and antifungal properties. Although the mechanism of action has not been fully elucidated thimerosal inhibits sulfhydryl-containing active site of various enzymes and binds to sulfhydryl compounds such as glutathione cysteine and SH groups of proteins. In addition thimerosal activates the InsP3 calcium channel on endoplasmic reticular membrane thereby triggering the release of calcium from intracellular stores resulting in a calcium-induced calcium-influx of extracellular calcium. Consequently thimerosal may induce or inhibit cellular functions dependent on calcium signaling.
  • 同义词
    Thiomersalate;Mercurothiolate
  • 通路
    GPCR/G Protein
  • 靶点
    Antibacterial
  • 受体
    Antibacterial
  • 研究领域
    Inflammation/Immunology
  • 适应症
    Septic; Fungal Infection

化学信息

  • CAS Number
    54-64-8
  • 分子量
    404.81
  • 分子式
    C9H9HgNaO2S
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:10 mM
  • SMILES
    [Na+].CC[Hg]SC1=CC=CC=C1C([O-])=O
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Li X et al. Toxicol Sci. 2014 Jun;139(2):452-65.
产品手册
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