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P516-0475

CAS No. 1359627-33-0

P516-0475 ( P516-0475; P5160475; P516 0475 )

产品货号. M11475 CAS No. 1359627-33-0

P516-0475 is a novel chemical inducer of Streptococcus quorum sensing acts by inhibiting the pheromone-degrading endopeptidase PepO (IC50=10 uM).

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥7857 有现货
50MG ¥16038 有现货
100MG ¥20250 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    P516-0475
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    P516-0475 is a novel chemical inducer of Streptococcus quorum sensing acts by inhibiting the pheromone-degrading endopeptidase PepO (IC50=10 uM).
  • 产品描述
    P516-0475 is a novel chemical inducer of Streptococcus quorum sensing acts by inhibiting the pheromone-degrading endopeptidase PepO (IC50=10 uM); specifically induces expression of Rgg2/3-regulated genes in the presence of SHP pheromones at concentrations lower than typically required for QS induction; P516-0475 directly inhibits recombinant PepO in vitro as an uncompetitive inhibitor, induces QS by stabilizing SHP pheromones in culture.
  • 同义词
    P516-0475; P5160475; P516 0475
  • 通路
    GPCR/G Protein
  • 靶点
    Antibacterial
  • 受体
    Antibacterial
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    1359627-33-0
  • 分子量
    315.33
  • 分子式
    C15H17N5O3
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    O=C(C1=C2N(N=N1)C3=C(C=C(C)C=C3)NC2=O)NCCCOC
  • 化学全称
    N-(3-methoxypropyl)-7-methyl-4-oxo-4,5-dihydro-[1,2,3]triazolo[1,5-a]quinoxaline-3-carboxamide

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Pérez Morales TG, et al. J Biol Chem. 2018 Jan 19;293(3):931-940.
产品手册
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