• 咨询热线
    客服服务热线 13671568941/15317326293
  • 在线咨询
  • 微信客服
    微信客服
  • 公众号
    扫码关注公众号

RNPA1000

CAS No. 359600-10-5

RNPA1000 ( RNPA-1000 )

产品货号. M14235 CAS No. 359600-10-5

RNPA1000 is a potent, specific small molecule inhibitor of S. aureus RnpA RNA degradation activity (IC50=100-125 uM).

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
50MG ¥5929 有现货
100MG ¥8829 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    RNPA1000
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    RNPA1000 is a potent, specific small molecule inhibitor of S. aureus RnpA RNA degradation activity (IC50=100-125 uM).
  • 产品描述
    RNPA1000 is a potent, specific small molecule inhibitor of S. aureus RnpA RNA degradation activity (IC50=100-125 uM), limits S. aureus mRNA turnover and growth; does not affect the activity of the E. coli RNase HI, RNase A, RNase I or in-house purified S. aureus RNase J1 at 750 uM; also limits growth of other important Gram-positive bacterial pathogens, exhibits antimicrobial efficacy against biofilm associated S. aureus (S. aureus MRSA USA100 strain MIC=26 ug/mL) and protects against the S. aureus pathogenesis in an animal model of infection.
  • 同义词
    RNPA-1000
  • 通路
    GPCR/G Protein
  • 靶点
    Antibacterial
  • 受体
    Antibacterial
  • 研究领域
    Infection
  • 适应症
    ——

化学信息

  • CAS Number
    359600-10-5
  • 分子量
    464.31
  • 分子式
    C23H18BrN3O3
  • 纯度
    >98% (HPLC)
  • 溶解度
    10 mM in DMSO
  • SMILES
    CC1=CC(=C(N1C2=CC=C(C=C2)C(=O)O)C)C=C(C#N)C(=O)NC3=CC(=CC=C3)Br
  • 化学全称
    Benzoic acid, 4-[3-[3-[(3-bromophenyl)amino]-2-cyano-3-oxo-1-propen-1-yl]-2,5-dimethyl-1H-pyrrol-1-yl]-

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Olson PD, et al. PLoS Pathog. 2011 Feb 10;7(2):e1001287.
2. Eidem TM, et al.
产品手册
关联产品
  • Vancomycin

    An antibiotic used to treat a number of bacterial infections that acts by inhibiting proper cell wall synthesis.

  • ML406

    ML406 is a small molecule Mtb bioA (DAPA synthase) enzyme inhibitor (IC50=30 nM) that shows anti-tubercular activity.

  • Rifamycin sodium sal...

    Rifamycin is an antibiotic that inhibits bacterial DNA-dependent RNA polymerase. It is effective against Gram-positive bacteria.