TP-238 ( TP238 )

产品货号. M17062 CAS No. ——

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

TP-238
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

TP-238 (TP238) is a CECR2/BPTF bromodomains chemical probe with IC50 of 30nM against CECR2 and 350nM against BPTF in an alphascreen assay.
产品描述

TP-238 (TP238) is a CECR2/BPTF bromodomains chemical probe with IC50 of 30nM against CECR2 and 350nM against BPTF in an alphascreen assay, KD of 10nM for CECR2 and 120nM for BPTF in ITC assays; TP-238 has been profiled against the panel of 338 kinases and showed no activity at 1 uM, the closest off-target bromodomain inhibition is BRD9 with IC50 of 1.4 uM.
同义词

TP238
通路

Chromatin/Epigenetic
靶点

Bromodomain
受体

Bromodomain
研究领域

——
适应症

——

CAS Number

——
分子量

458.58
分子式

C22H30N6O3S
纯度

>98% (HPLC)
溶解度

——
SMILES

O=S(C1=NC(C2=CC=C(OCCCN(C)C)C=C2)=CC(NCCCN3N=CC=C3)=N1)(C)=O
化学全称

N-(3-(1H-pyrazol-1-yl)propyl)-6-(4-(3-(dimethylamino)propoxy)phenyl)-2-(methylsulfonyl)pyrimidin-4-amine

计算器

产品手册

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