TCID ( UCH-L3 Inhibitor )

产品货号. M13979 CAS No. 30675-13-9

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

TCID
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

TCID is a selective ubiquitin C-terminal hydrolase-L3 (UCH-L3) inhibitor with IC50 of 0.6 uM.
产品描述

TCID is a selective ubiquitin C-terminal hydrolase-L3 (UCH-L3) inhibitor with IC50 of 0.6 uM, displays >100-fold selectivity over UCH-L1; diminishes glycine transporter GlyT2 ubiquitination in brain stem and spinal cord primary neurons.
同义词

UCH-L3 Inhibitor
通路

Proteasome/Ubiquitin
靶点

DUB
受体

UCH-L1;UCH-L3
研究领域

Other Indications
适应症

——

CAS Number

30675-13-9
分子量

283.90
分子式

C9H2Cl4O2
纯度

>98% (HPLC)
溶解度

DMSO: 14.2 mg/mL (50 mM) （ < 1 mg/ml refers to the product slightly soluble or insoluble )
SMILES

C1C(=O)C2=C(C1=O)C(=C(C(=C2Cl)Cl)Cl)Cl
化学全称

4,5,6,7-Tetrachloro-1H-Indene-1,3(2H)-dione

1. Liu Y, et al. Chem Biol. 2003 Sep;10(9):837-46.
2. de Juan-Sanz J, et al. PLoS One. 2013;8(3):e58863.

计算器

产品手册

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TCID

TCID is a selective ubiquitin C-terminal hydrolase-L3 (UCH-L3) inhibitor with IC50 of 0.6 uM.