Scoulerine ( (-)-Scoulerine; Discretamine )

产品货号. M29229 CAS No. 6451-73-6

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Scoulerine
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Scoulerine is an inhibitor of ?-site amyloid precursor protein cleaving enzyme 1(BACE1). Scoulerine a potent antimitotic compound that inhibits proliferation, arrests cell cycle, and induces apoptosis in cancer cells.
产品描述

Scoulerine is an inhibitor of ?-site amyloid precursor protein cleaving enzyme 1(BACE1). Scoulerine a potent antimitotic compound that inhibits proliferation, arrests cell cycle, and induces apoptosis in cancer cells.(In Vitro):Scoulerine shows significant cytotoxic effects against both two cancer cell lines (Caco-2 and Hep-G2 cancer cells), with IC50 values 6.44 ± 0.87 and 4.57 ± 0.42, respectively. Scoulerine shows antiplasmodial activity with IC50 values of 5.4 μM and 3.1 μM against the antifolate sensitive and the multidrug resistant P. falciparum strains: TM4/8.2 and K1CB1, respectively.
同义词

(-)-Scoulerine; Discretamine
通路

Apoptosis
靶点

Apoptosis
受体

Apoptosis
研究领域

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适应症

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计算器

产品手册

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