021-51111890
购物车（）
sales@molnova.cn
Ruzasvir
CAS No. 1613081-64-3
Ruzasvir ( MK-8408;MK 8408;MK8408 )
产品货号. M12336 CAS No. 1613081-64-3
A potent, pan-genotype HCV NS5A inhibitor.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥3888 | 有现货 |
|
| 10MG | ￥5565 | 有现货 |
|
| 25MG | ￥8748 | 有现货 |
|
| 50MG | ￥11988 | 有现货 |
|
| 100MG | 获取报价 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称Ruzasvir
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述A potent, pan-genotype HCV NS5A inhibitor.
-
产品描述A potent, pan-genotype HCV NS5A inhibitor with replicon EC90 of 0.003, 0.016, 0.067, 0.036, 0.007, and 0.007 nM for GT1a, GT1a L31V, GT1a Y93H, GT2b, GT3a, and Gt4a, respectively.HCV Infection Phase 2 Clinical
-
同义词MK-8408;MK 8408;MK8408
-
通路Microbiology/Virology
-
靶点HCV
-
受体HCV
-
研究领域Infection
-
适应症HCV Infection
化学信息
-
CAS Number1613081-64-3
-
分子量947.10
-
分子式C49H55FN10O7S
-
纯度>98% (HPLC)
-
溶解度——
-
SMILESFC1=C(C(N2[C@H](C3=CN=C(C4CC4)S3)O5)=CC6=C2C=CC(C7=CN=C(C8N(C(C(NC(OC)=O)C(C)C)=O)CCC8)N7)=C6)C5=CC(C9=CN=C([C@H]%10N(C(C(NC(OC)=O)C(C)C)=O)CCC%10)N9)=C1
-
化学全称Dimethyl N,N'-([(6S)-6-(2-cyclopropyl-1,3-thiazol-5-yl)-1-fluoro-6H-indolo[1,2-c][1,3]benzoxazine-3,10-diyl]bis{(1H-imidazole-4,2-diyl)[(2S)-pyrrolidine-2,1- diyl][(2S)-3-methyl-1-oxobutane-1,2-diyl]})dicarbamate
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1. Tong L, et al. J Med Chem. 2017 Jan 12;60(1):290-306.
2. Wyles D, et al. Hepatology. 2017 Dec;66(6):1794-1804.
3. Lawitz E, et al. Lancet Gastroenterol Hepatol. 2017 Nov;2(11):814-823.
2. Wyles D, et al. Hepatology. 2017 Dec;66(6):1794-1804.
3. Lawitz E, et al. Lancet Gastroenterol Hepatol. 2017 Nov;2(11):814-823.
产品手册
关联产品
-
AM281
AM 281, a cannabinoid antagonist, reduces neurologic dysfunction and mortality rate after cecal ligation and puncture in rats.
-
Balapiravir
The prodrug of R1479, a potent, specific and oral HCV NS5B polymerase inhibitor.
-
Boceprevir
A potent, selective, orally bioavailable HCV NS3 protease with Ki of 14 nM, EC90 of 350 nM in cell replicon assays.
