Ravidasvir ( PPI-668;BI 238630 )

产品货号. M10976 CAS No. 1242087-93-9

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Ravidasvir
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Ravidasvir (PPI-668;BI 238630) is a potent pan-genotypic HCV NS5A inhibitor with IC50 of 0.12/0.01/1.14 nM for HCV gt-1a/1b/3a in replicon luciferase assay.
产品描述

Ravidasvir (PPI-668;BI 238630) is a potent pan-genotypic HCV NS5A inhibitor with IC50 of 0.12/0.01/1.14 nM for HCV gt-1a/1b/3a in replicon luciferase assay; has been well tolerated and shown high sustained viral response rates as a key component in all-oral combination regimens in multiple human clinical trials.HCV Infection Phase 3 Clinical
同义词

PPI-668;BI 238630
通路

Microbiology/Virology
靶点

HCV
受体

HCV
研究领域

Infection
适应症

HCV Infection

CAS Number

1242087-93-9
分子量

762.91
分子式

C42H50N8O6
纯度

>98% (HPLC)
溶解度

——
SMILES

CC(C)C(C(=O)N1CCCC1C2=NC3=C(N2)C=C(C=C3)C4=CC5=C(C=C4)C=C(C=C5)C6=CN=C(N6)C7CCCN7C(=O)C(C(C)C)NC(=O)OC)NC(=O)OC
化学全称

Methyl N-[(2S)-1-{(2S)-2-[5-(6-{2-[(2S)-1-{(2S)-2-[(methoxycarbonyl)amino]-3-methylbutanoyl}pyrrolidin-2-yl]-1H-imidazol-4-yl}naphthalen-2-yl)-1H-benzimidazol-2-yl]pyrrolidin-1-yl}-3-methyl-1-oxobutan-2-yl]carbamate

1. Zhong M, et al. Bioorg Med Chem Lett. 2016 Sep 15;26(18):4508-12.

计算器

产品手册

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