Azvudine ( RO 0622 )

产品货号. M10071 CAS No. 1011529-10-4

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Azvudine
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Azvudine (RO 0622) is a potent HCV NS5B RNA polymerase inhibitor.
产品描述

Azvudine (RO 0622) is a potent HCV NS5B RNA polymerase inhibitor, inhibits HCV replication in the replicon system with IC50 of 24 nM; inhibits RNA synthesis by HCV polymerases from either HCV genotypes 1a and 1b or containing S96T or S282T point mutations (IC50=10-100 nM).
同义词

RO 0622
通路

Microbiology/Virology
靶点

HCV
受体

HCV
研究领域

——
适应症

——

CAS Number

1011529-10-4
分子量

286.22
分子式

C9H11FN6O4
纯度

>98% (HPLC)
溶解度

——
SMILES

O=C1N=C(N)C=CN1[C@H]2[C@@H](F)[C@@H]([C@](CO)(N=[N+]=[N-])O2)O
化学全称

4-amino-1-[(2R,3S,4R,5R)-5-azido-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one

1. Klumpp K, et al. J Biol Chem. 2008 Jan 25;283(4):2167-75.

计算器

产品手册

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