Ralaniten ( EPI-506 )

产品货号. M10744 CAS No. 1203490-23-6

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Ralaniten
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Ralaniten (EPI-506) is a novel small-molecule inhibitor of androgen receptor (AR) N-terminal domain inhibitor for the treatment of advanced prostate cancer.
产品描述

Ralaniten (EPI-506) is a novel small-molecule inhibitor of androgen receptor (AR) N-terminal domain inhibitor for the treatment of advanced prostate cancer; AR NTD-targeting agents have the potential to overcome shortcomings of current hormonal therapies by inhibiting all forms of AR-mediated transcriptional activity, and as a result, may affect a broader AR population including mutational and splice variant ARs.Prostate Cancer Phase 2 Clinical
同义词

EPI-506
通路

Endocrinology/Hormones
靶点

Estrogen Receptor/ERR
受体

Estrogen Receptor/ERR
研究领域

Cancer
适应症

Prostate Cancer

CAS Number

1203490-23-6
分子量

394.89
分子式

C21H27ClO5
纯度

>98% (HPLC)
溶解度

——
SMILES

CC(C)(C1=CC=C(C=C1)OCC(CO)O)C2=CC=C(C=C2)OCC(CCl)O
化学全称

(2R)-3-[4-(2-{4-[(2S)-3-chloro- 2-hydroxypropoxy]phenyl}propan-2-yl)phenoxy]propane- 1,2-diol

1. Antonarakis ES, et al. Oncologist. 2016 Dec;21(12):1427-1435.

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