XCT790
CAS No. 725247-18-7
XCT790 ( XCT 790;XCT-790 )
产品货号. M15777 CAS No. 725247-18-7
A potent and selective ERRα inverse agonist with IC50 of 300-500 nM in transient transfection assays.
纯度: >98% (HPLC)
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥478 | 有现货 |
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10MG | ¥794 | 有现货 |
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25MG | ¥1531 | 有现货 |
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50MG | ¥2795 | 有现货 |
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100MG | ¥4155 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称XCT790
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述A potent and selective ERRα inverse agonist with IC50 of 300-500 nM in transient transfection assays.
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产品描述A potent and selective ERRα inverse agonist with IC50 of 300-500 nM in transient transfection assays; shows no significant antagonist activity on related nuclear receptors (ERRγ or ERα, LXRα, LXRβ, FXR, PPARα, PPARδ, PPARγ, Nurr1, RARα, RORα, and RXRα) at 10 uM; inhibits PGC-1α regulation of ERRα and ERRα target gene expression; inhibits proliferation in cellular models of breast cancer.
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同义词XCT 790;XCT-790
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通路Endocrinology/Hormones
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靶点Estrogen Receptor/ERR
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受体ERRα
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研究领域Cancer
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适应症——
化学信息
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CAS Number725247-18-7
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分子量596.42
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分子式C23H13F9N4O3S
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纯度>98% (HPLC)
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溶解度DMSO: 21 mg/mL
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SMILESO=C(NC1=NN=C(C(F)(F)F)S1)/C(C#N)=C/C2=CC=C(OCC3=CC=C(C(F)(F)F)C=C3C(F)(F)F)C(OC)=C2
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化学全称2-Propenamide, 3-[4-[[2,4-bis(trifluoromethyl)phenyl]methoxy]-3-methoxyphenyl]-2-cyano-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]-
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
2. Busch BB, et al. J Med Chem. 2004 Nov 4;47(23):5593-6.
3. Lanvin O, et al. J Biol Chem. 2007 Sep 28;282(39):28328-34.
4. Chang CY, et al. Cancer Cell. 2011 Oct 18;20(4):500-10.
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