XCT790 ( XCT 790;XCT-790 )

产品货号. M15777 CAS No. 725247-18-7

A potent and selective ERRα inverse agonist with IC50 of 300-500 nM in transient transfection assays.

纯度: >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

规格	价格/人民币	库存	数量
5MG	￥478	有现货
10MG	￥794	有现货
25MG	￥1531	有现货
50MG	￥2795	有现货
100MG	￥4155	有现货
200MG	获取报价	有现货
500MG	获取报价	有现货
1G	获取报价	有现货

拼团产品询价大包装询价加入购物车

生物学信息

产品名称

XCT790
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

A potent and selective ERRα inverse agonist with IC50 of 300-500 nM in transient transfection assays.
产品描述

A potent and selective ERRα inverse agonist with IC50 of 300-500 nM in transient transfection assays; shows no significant antagonist activity on related nuclear receptors (ERRγ or ERα, LXRα, LXRβ, FXR, PPARα, PPARδ, PPARγ, Nurr1, RARα, RORα, and RXRα) at 10 uM; inhibits PGC-1α regulation of ERRα and ERRα target gene expression; inhibits proliferation in cellular models of breast cancer.
同义词

XCT 790;XCT-790
通路

Endocrinology/Hormones
靶点

Estrogen Receptor/ERR
受体

ERRα
研究领域

Cancer
适应症

——

化学信息

CAS Number

725247-18-7
分子量

596.42
分子式

C23H13F9N4O3S
纯度

>98% (HPLC)
溶解度

DMSO: 21 mg/mL
SMILES

O=C(NC1=NN=C(C(F)(F)F)S1)/C(C#N)=C/C2=CC=C(OCC3=CC=C(C(F)(F)F)C=C3C(F)(F)F)C(OC)=C2
化学全称

2-Propenamide, 3-[4-[[2,4-bis(trifluoromethyl)phenyl]methoxy]-3-methoxyphenyl]-2-cyano-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]-

运输与储存

储存条件

(-20℃)
运输条件

With Ice Pack
稳定性

≥ 2 years

参考文献

1. Willy PJ, et al. Proc Natl Acad Sci U S A. 2004 Jun 15;101(24):8912-7.

2. Busch BB, et al. J Med Chem. 2004 Nov 4;47(23):5593-6.

3. Lanvin O, et al. J Biol Chem. 2007 Sep 28;282(39):28328-34.

4. Chang CY, et al. Cancer Cell. 2011 Oct 18;20(4):500-10.

计算器

浓度计算器

摩尔计算器

分子量计算器

产品手册

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