021-51111890
购物车（）
sales@molnova.cn
XCT790
CAS No. 725247-18-7
XCT790 ( XCT 790;XCT-790 )
产品货号. M15777 CAS No. 725247-18-7
A potent and selective ERRα inverse agonist with IC50 of 300-500 nM in transient transfection assays.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥478 | 有现货 |
|
| 10MG | ￥794 | 有现货 |
|
| 25MG | ￥1531 | 有现货 |
|
| 50MG | ￥2795 | 有现货 |
|
| 100MG | ￥4155 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称XCT790
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述A potent and selective ERRα inverse agonist with IC50 of 300-500 nM in transient transfection assays.
-
产品描述A potent and selective ERRα inverse agonist with IC50 of 300-500 nM in transient transfection assays; shows no significant antagonist activity on related nuclear receptors (ERRγ or ERα, LXRα, LXRβ, FXR, PPARα, PPARδ, PPARγ, Nurr1, RARα, RORα, and RXRα) at 10 uM; inhibits PGC-1α regulation of ERRα and ERRα target gene expression; inhibits proliferation in cellular models of breast cancer.
-
同义词XCT 790;XCT-790
-
通路Endocrinology/Hormones
-
靶点Estrogen Receptor/ERR
-
受体ERRα
-
研究领域Cancer
-
适应症——
化学信息
-
CAS Number725247-18-7
-
分子量596.42
-
分子式C23H13F9N4O3S
-
纯度>98% (HPLC)
-
溶解度DMSO: 21 mg/mL
-
SMILESO=C(NC1=NN=C(C(F)(F)F)S1)/C(C#N)=C/C2=CC=C(OCC3=CC=C(C(F)(F)F)C=C3C(F)(F)F)C(OC)=C2
-
化学全称2-Propenamide, 3-[4-[[2,4-bis(trifluoromethyl)phenyl]methoxy]-3-methoxyphenyl]-2-cyano-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]-
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
2. Busch BB, et al. J Med Chem. 2004 Nov 4;47(23):5593-6.
3. Lanvin O, et al. J Biol Chem. 2007 Sep 28;282(39):28328-34.
4. Chang CY, et al. Cancer Cell. 2011 Oct 18;20(4):500-10.
产品手册
关联产品
-
Ulipristal acetate
Ulipristal acetate(CDB2914) is a novel selective progesterone receptor modulator (SPRM) for the treatment of benign gynecological conditions such as uterine myoma.
-
GLL 398
GLL 398 is an orally active and selective degrader of estrogen receptor with an IC50 of 1.14 nM. GLL 398 blocks tumor growth in xenograft breast cancer models.
-
Chrysin
Chrysin is mainly found in passion flowers, honey, and propolis acts as a potential therapeutic and preventive agent to inhibit proliferation and invasion of various human cancer cells.
