Pibrentasvir
CAS No. 1353900-92-1
Pibrentasvir ( ABT-530 )
产品货号. M11442 CAS No. 1353900-92-1
Pibrentasvir (ABT-530) is a novel and pan-genotypic HCV NS5A inhibitor with EC50 of 1.4-5.0 pM against HCV replicons containing NS5A genotypes 1-6.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥794 | 有现货 |
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10MG | ¥1199 | 有现货 |
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25MG | ¥2373 | 有现货 |
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50MG | ¥3540 | 有现货 |
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100MG | ¥5233 | 有现货 |
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200MG | 获取报价 | 有现货 |
|
500MG | 获取报价 | 有现货 |
|
1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Pibrentasvir
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Pibrentasvir (ABT-530) is a novel and pan-genotypic HCV NS5A inhibitor with EC50 of 1.4-5.0 pM against HCV replicons containing NS5A genotypes 1-6.
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产品描述Pibrentasvir (ABT-530) is a novel and pan-genotypic HCV NS5A inhibitor with EC50 of 1.4-5.0 pM against HCV replicons containing NS5A genotypes 1-6; demonstrates potent antiviral activity and acceptable safety during 3-day monotherapy in patients with HCV genotype 1 infection, with or without compensated cirrhosis.HCV Infection Phase 2 Clinical
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同义词ABT-530
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通路Microbiology/Virology
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靶点HCV
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受体HCVNS5A
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研究领域Infection
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适应症HCV Infection
化学信息
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CAS Number1353900-92-1
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分子量1113.20
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分子式C57H65F5N10O8
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纯度>98% (HPLC)
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溶解度DMSO: 60 mg/mL, need ultrasonic ( < 1 mg/ml refers to the product slightly soluble or insoluble )
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SMILESFC1=CC=C(C2CCN(C3=C(F)C=C(N4[C@@H](C5=C(F)C=C6C(N=C([C@H]7N(C([C@@H](NC(OC)=O)[C@H](OC)C)=O)CCC7)N6)=C5)CC[C@@H]4C8=C(F)C=C9C(N=C([C@H]%10N(C([C@@H](NC(OC)=O)[C@H](OC)C)=O)CCC%10)N9)=C8)C=C3F)CC2)C=C1
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化学全称Dimethyl ((2S,2'S,3R,3'R)-((2S,2'S)-(((2R,5R)-1-(3,5-difluoro-4-(4-(4-fluorophenyl)piperidin-1-yl)phenyl)pyrrolidine-2,5-diyl)bis(6-fluoro-1H-benzo[d]imidazole-5,2-diyl))bis(pyrrolidine-2,1-diyl))bis(3-methoxy-1-oxobutane-1,2-diyl))dicarbamate
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Lawitz EJ, et al. Antimicrob Agents Chemother. 2015 Dec 28;60(3):1546-55.
2. Poordad F, et al. Liver Int. 2016 Aug;36(8):1125-32.
3. Ng TI, et al. Antimicrob Agents Chemother. 2017 Apr 24;61(5). pii: e02558-16.
2. Poordad F, et al. Liver Int. 2016 Aug;36(8):1125-32.
3. Ng TI, et al. Antimicrob Agents Chemother. 2017 Apr 24;61(5). pii: e02558-16.
产品手册
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