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PRX-08066

CAS No. 866206-54-4

PRX-08066 ( —— )

产品货号. M24869 CAS No. 866206-54-4

PRX-08066 is a selective 5-hydroxytryptamine receptor 2B (5-HT2BR, IC50= 3.4 nM) antagonist that induces selective vasodilation of pulmonary arteries.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥988 有现货
10MG ¥1442 有现货
25MG ¥2989 有现货
50MG ¥4447 有现货
100MG ¥6383 有现货
500MG ¥13203 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    PRX-08066
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    PRX-08066 is a selective 5-hydroxytryptamine receptor 2B (5-HT2BR, IC50= 3.4 nM) antagonist that induces selective vasodilation of pulmonary arteries.
  • 产品描述
    PRX-08066 is a selective 5-hydroxytryptamine receptor 2B (5-HT2BR, IC50= 3.4 nM) antagonist that induces selective vasodilation of pulmonary arteries.
  • 同义词
    ——
  • 通路
    Endocrinology/Hormones
  • 靶点
    5-HT Receptor
  • 受体
    5-HT2B
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    866206-54-4
  • 分子量
    401.9
  • 分子式
    C19H17ClFN5S
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:7 mg/mL (17.42 mM; Need ultrasonic)
  • SMILES
    C1CN(CCC1NC2=C3C=C(SC3=NC=N2)Cl)CC4=CC(=C(C=C4)F)C#N
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Porvasnik SL, et al. PRX-08066, a novel 5-hydroxytryptamine receptor 2B antagonist, reduces monocrotaline-induced pulmonary arterial hypertension and right ventricular hypertrophy in rats. J Pharmacol Exp Ther. 2010 Aug;334(2):364-72.
产品手册
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