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PR-619

CAS No. 2645-32-1

PR-619 ( 2,6-Diamino-3,5-dithiocyanopyridine; DUB Inhibitor V )

产品货号. M13810 CAS No. 2645-32-1

PR-619 is a non-selective, reversible inhibitor of the deubiquitinylating enzymes (DUBs) with EC50 of 1-20 μM in a cell-free assay.

纯度: >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥365 有现货
10MG ¥583 有现货
25MG ¥1013 有现货
50MG ¥1588 有现货
100MG ¥2406 有现货
200MG ¥3613 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    PR-619
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    PR-619 is a non-selective, reversible inhibitor of the deubiquitinylating enzymes (DUBs) with EC50 of 1-20 μM in a cell-free assay.
  • 产品描述
    PR-619 is a non-selective, reversible inhibitor of the deubiquitinylating enzymes (DUBs) with EC50 of 1-20 μM in a cell-free assay.
  • 同义词
    2,6-Diamino-3,5-dithiocyanopyridine; DUB Inhibitor V
  • 通路
    Proteasome/Ubiquitin
  • 靶点
    DUB
  • 受体
    JOSD2; SENP6 core; UCH-L3; USP4; USP8
  • 研究领域
    Cancer
  • 适应症
    ——

化学信息

  • CAS Number
    2645-32-1
  • 分子量
    223.33
  • 分子式
    C7H5N5S2
  • 纯度
    >98%(HPLC)
  • 溶解度
    DMSO: 45 mg/mL (201.54 mM)
  • SMILES
    N#CSC1=C(N)N=C(N)C(SC#N)=C1
  • 化学全称
    (2,6-diamino-5-thiocyanatopyridin-3-yl) thiocyanate

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Altun M, et al. Chem Biol, 2011, 18(11), 1401-1412.
产品手册
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