MF-094 ( MF094 )

产品货号. M13591 CAS No. 2241025-68-1

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

MF-094
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

MF-094 (MF094) is a potent, highly selective inhibitor of ubiquitin specific protease 30 (USP30) with IC50 of 0.12 uM.
产品描述

MF-094 (MF094) is a potent, highly selective inhibitor of ubiquitin specific protease 30 (USP30) with IC50 of 0.12 uM, demonstrates <30% inhibitory activity for a panel of 22 USPs assays at 10 uM; increases protein ubiquitination and accelerates mitophagy.
同义词

MF094
通路

Proteasome/Ubiquitin
靶点

DUB
受体

DUB
研究领域

——
适应症

——

CAS Number

2241025-68-1
分子量

535.70
分子式

C30H37N3O4S
纯度

>98% (HPLC)
溶解度

DMSO : 125 mg/mL 233.34 mM
SMILES

CC(C)(C)NS(=O)(=O)C1=CC=CC2=C1C=CC=C2NC(=O)C(CC3=CC=CC=C3)NC(=O)C4CCCCC4
化学全称

(S)-N-(1-((5-(N-(tert-butyl)sulfamoyl)naphthalen-1-yl)amino)-1-oxo-3-phenylpropan-2-yl)cyclohexanecarboxamide

1. Kluge AF, et al. Bioorg Med Chem Lett. 2018 May 8. pii: S0960-894X(18)30402-5.

计算器

产品手册

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