B-AP15 ( b-AP15;USP14 Inhibitor III; UCHL5UCH37 Inhibitor II; NSC687852. )

产品货号. M10064 CAS No. 1009817-63-3

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

B-AP15
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

B-AP15(NSC687852) is a specific inhibitor of the deubiquitinating enzymes UCHL5 and Usp14 of the 26S proteasome.
产品描述

B-AP15(NSC687852) is a specific inhibitor of the deubiquitinating enzymes UCHL5 and Usp14 of the 26S proteasome. It blocks the deubiquitinating activity of the 26S proteasome.
同义词

b-AP15;USP14 Inhibitor III; UCHL5UCH37 Inhibitor II; NSC687852.
通路

Proteasome/Ubiquitin
靶点

DUB
受体

UCH-L5
研究领域

Cancer
适应症

——

CAS Number

1009817-63-3
分子量

419.39
分子式

C22H17N3O6
纯度

>98%(HPLC)
溶解度

DMSO: 48 mg/mL warmed (114.45 mM)
SMILES

O=C1/C(CN(C(C=C)=O)C/C1=C\C2=CC=C([N+]([O-])=O)C=C2)=C/C3=CC=C([N+]([O-])=O)C=C3
化学全称

(3E,5E)-1-acryloyl-3,5-bis(4-nitrobenzylidene)piperidin-4-one.

1. D'Arcy P, et al. Nat Med. 2011 Nov 6;17(12):1636-40.

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