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NecroX-7
CAS No. 1120333-38-1
NecroX-7 ( Necrosis inhibitor 7 )
产品货号. M10431 CAS No. 1120333-38-1
NecroX-7 is a small molecule necrosis modulator and potent antioxidant molecule.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 100MG | 获取报价 | 有现货 |
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| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称NecroX-7
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述NecroX-7 is a small molecule necrosis modulator and potent antioxidant molecule.
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产品描述NecroX-7 is a small molecule necrosis modulator and potent antioxidant molecule, which can be bound to some types of radicals and especially NAPQI; inhibits osteoclast differentiation by suppressing NF-κB activity and c-Fos expression, reduces hepatic necrosis secondary to IR injury in vivo; decreases t-BHP- and APAP-induced cell death and ROS/RNS formation in HepG2 human hepatocarcinoma and primary mouse hepatocytes, also protects mice from APAP-induced liver injury and lethality by binding directly to NAPQI.
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同义词Necrosis inhibitor 7
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通路Apoptosis
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靶点Apoptosis
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受体Apoptosis
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研究领域——
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适应症——
化学信息
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CAS Number1120333-38-1
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分子量439.57
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分子式C24H29N3O3S
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纯度>98% (HPLC)
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溶解度——
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SMILES——
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化学全称4-((7-((1-(methylsulfonyl)piperidin-4-yl)amino)-2-phenyl-1H-indol-5-yl)methyl)thiomorpholine 1,1-dioxide
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Choi JM, et al. Transplant Proc. 2010 Nov;42(9):3414-21.
2. Grootaert MO, et al. Atherosclerosis. 2016 Sep;252:166-74.
3. Lee DW, et al. Am J Physiol Heart Circ Physiol. 2011 Sep;301(3):H1004-14.
4. Park JH, et al. Antioxid Redox Signal. 2013 May 10;18(14):1713-22.
2. Grootaert MO, et al. Atherosclerosis. 2016 Sep;252:166-74.
3. Lee DW, et al. Am J Physiol Heart Circ Physiol. 2011 Sep;301(3):H1004-14.
4. Park JH, et al. Antioxid Redox Signal. 2013 May 10;18(14):1713-22.
产品手册
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