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Naronapride
CAS No. 860174-12-5
Naronapride ( ATI-7505 )
产品货号. M16233 CAS No. 860174-12-5
Naronapride (ATI-7505) is a potent, selective and orally active 5-HT4 receptor agonist with Ki of 1.4 nM.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥6140 | 有现货 |
|
| 50MG | ￥22559 | 有现货 |
|
| 100MG | ￥28512 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Naronapride
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Naronapride (ATI-7505) is a potent, selective and orally active 5-HT4 receptor agonist with Ki of 1.4 nM.
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产品描述Naronapride (ATI-7505) is a potent, selective and orally active 5-HT4 receptor agonist with Ki of 1.4 nM; displays negligible affinity for Kv11.1 channels (Ki=24,500 nM), and no effect on cardiac repolarization; shows potential for treatment of gastrointestinal motility disorders.Other Indication Phase 2 Clinical
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同义词ATI-7505
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通路Endocrinology/Hormones
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靶点5-HT Receptor
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受体5-HT Receptor
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研究领域Other Indications
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适应症Other Disease
化学信息
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CAS Number860174-12-5
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分子量537.10
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分子式C27H41ClN4O5
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纯度>98% (HPLC)
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溶解度——
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SMILESO=C(O[C@H]1CN2CCC1CC2)CCCCCN3C[C@H](OC)[C@H](NC(C4=CC(Cl)=C(N)C=C4OC)=O)CC3
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化学全称[(3R)-1-azabicyclo[2.2.2]octan-3-yl] 6-[(3S,4R)-4-[(4-amino-5-chloro-2-methoxybenzoyl)amino]-3-methoxypiperidin-1-yl]hexanoate
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Manabe N, et al. Expert Opin Investig Drugs. 2010 Jun;19(6):765-75.
2. Bowersox SS, et al. Drug Metab Dispos. 2011 Jul;39(7):1170-80.
3. Hoffman JM, et al. Gastroenterology. 2012 Apr;142(4):844-854.e4.
4. Camilleri M, et al. Neurogastroenterol Motil. 2007 Jan;19(1):30-8.
2. Bowersox SS, et al. Drug Metab Dispos. 2011 Jul;39(7):1170-80.
3. Hoffman JM, et al. Gastroenterology. 2012 Apr;142(4):844-854.e4.
4. Camilleri M, et al. Neurogastroenterol Motil. 2007 Jan;19(1):30-8.
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