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Naratriptan

CAS No. 143388-64-1

Naratriptan ( Naratriptan HCl; Amerge; Naramig; GR-85548A )

产品货号. M18015 CAS No. 143388-64-1

Naratriptan Hydrochloride is the hydrochloride salt form of naratriptan, a sulfonamide with selective serotonin (5-HT) 1 receptor agonistic activity and anti-migraine property.

纯度: 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
10MG ¥348 有现货
25MG ¥656 有现货
50MG ¥1094 有现货
100MG ¥1936 有现货
200MG ¥2414 有现货
500MG ¥3977 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Naratriptan
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Naratriptan Hydrochloride is the hydrochloride salt form of naratriptan, a sulfonamide with selective serotonin (5-HT) 1 receptor agonistic activity and anti-migraine property.
  • 产品描述
    Naratriptan Hydrochloride is the hydrochloride salt form of naratriptan, a sulfonamide with selective serotonin (5-HT) 1 receptor agonistic activity and anti-migraine property. Naratriptan hydrochloride binds selectively and with high affinity to the 5-HT1D and 5-HT1B receptor subtypes. Activation of these 5-HT1D/B receptors located on intracranial blood vessels leads to vasoconstriction and provides relief of migraine headaches. Naratriptan hydrochloride may also exerts its effect by stimulation of 5-HT1D/1B receptors on sensory nerve endings in the trigeminal system thereby decreasing the release of pro-inflammatory neuropeptides.
  • 同义词
    Naratriptan HCl; Amerge; Naramig; GR-85548A
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    5-HT1
  • 研究领域
    Neurological Disease
  • 适应症
    ——

化学信息

  • CAS Number
    143388-64-1
  • 分子量
    371.93
  • 分子式
    C17H25N3O2S·HCl
  • 纯度
    98%
  • 溶解度
    DMSO : ≥ 35 mg/mL; 94.10 mM
  • SMILES
    CNS(=O)(=O)CCc1cc2c(cc1)[nH]cc2C1CCN(CC1)C.Cl
  • 化学全称
    N-Methyl-2-[3-(1-methylpiperidin-4-yl)-1H-indol-5-yl]ethanesulfonamide hydrochloride

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Sattar M, Hadgraft J, Lane ME.Int J Pharm. 2015 Sep 30;493(1-2):146-51.
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