Naratriptan
CAS No. 143388-64-1
Naratriptan ( Naratriptan HCl; Amerge; Naramig; GR-85548A )
产品货号. M18015 CAS No. 143388-64-1
Naratriptan Hydrochloride is the hydrochloride salt form of naratriptan, a sulfonamide with selective serotonin (5-HT) 1 receptor agonistic activity and anti-migraine property.
纯度: 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
10MG | ¥348 | 有现货 |
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25MG | ¥656 | 有现货 |
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50MG | ¥1094 | 有现货 |
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100MG | ¥1936 | 有现货 |
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200MG | ¥2414 | 有现货 |
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500MG | ¥3977 | 有现货 |
|
1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Naratriptan
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Naratriptan Hydrochloride is the hydrochloride salt form of naratriptan, a sulfonamide with selective serotonin (5-HT) 1 receptor agonistic activity and anti-migraine property.
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产品描述Naratriptan Hydrochloride is the hydrochloride salt form of naratriptan, a sulfonamide with selective serotonin (5-HT) 1 receptor agonistic activity and anti-migraine property. Naratriptan hydrochloride binds selectively and with high affinity to the 5-HT1D and 5-HT1B receptor subtypes. Activation of these 5-HT1D/B receptors located on intracranial blood vessels leads to vasoconstriction and provides relief of migraine headaches. Naratriptan hydrochloride may also exerts its effect by stimulation of 5-HT1D/1B receptors on sensory nerve endings in the trigeminal system thereby decreasing the release of pro-inflammatory neuropeptides.
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同义词Naratriptan HCl; Amerge; Naramig; GR-85548A
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通路Others
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靶点Other Targets
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受体5-HT1
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研究领域Neurological Disease
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适应症——
化学信息
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CAS Number143388-64-1
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分子量371.93
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分子式C17H25N3O2S·HCl
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纯度98%
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溶解度DMSO : ≥ 35 mg/mL; 94.10 mM
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SMILESCNS(=O)(=O)CCc1cc2c(cc1)[nH]cc2C1CCN(CC1)C.Cl
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化学全称N-Methyl-2-[3-(1-methylpiperidin-4-yl)-1H-indol-5-yl]ethanesulfonamide hydrochloride
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Sattar M, Hadgraft J, Lane ME.Int J Pharm. 2015 Sep 30;493(1-2):146-51.
产品手册
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