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GSK163090

CAS No. 844903-58-8

GSK163090 ( —— )

产品货号. M24834 CAS No. 844903-58-8

GSK163090 is a specific and orally active 5-HT1A/B/D receptor antagonist (pKis: 9.4/8.5/9.7, and 6.3/6.7 for 5-HT1A/B/D, and dopamine D2/D3).

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥1280 有现货
10MG ¥2179 有现货
25MG ¥3669 有现货
50MG ¥5395 有现货
100MG 获取报价 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    GSK163090
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    GSK163090 is a specific and orally active 5-HT1A/B/D receptor antagonist (pKis: 9.4/8.5/9.7, and 6.3/6.7 for 5-HT1A/B/D, and dopamine D2/D3).
  • 产品描述
    GSK163090 is a specific and orally active 5-HT1A/B/D receptor antagonist (pKis: 9.4/8.5/9.7, and 6.3/6.7 for 5-HT1A/B/D, and dopamine D2/D3).
  • 同义词
    ——
  • 通路
    Endocrinology/Hormones
  • 靶点
    5-HT Receptor
  • 受体
    5-HT1A;5-HT1B;5-HT1D;Dopamine
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    844903-58-8
  • 分子量
    415.5
  • 分子式
    C25H29N5O
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:14.29 mg/mL (34.39 mM; Need ultrasonic)
  • SMILES
    Cc1ccc(c(N2CCN(CCc3cccc(N(CCN4)C4=O)c3)CC2)ccc2)c2n1
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Leslie CP, et al. Discovery of 1-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-2-imidazolidinone (GSK163090), a Potent, selective, and orally active 5-HT1A/B/D receptor antagonist. J Med Chem. 2010 Dec 9;53(23):8228-8240.
产品手册
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