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NCT-502
CAS No. 1542213-00-2
NCT-502 ( N-(4,6-dimethylpyridin-2-yl)-4-[5-(trifluoromethyl)pyridin-2-yl]piperazine-1-carbothioamide )
产品货号. M26771 CAS No. 1542213-00-2
NCT-502 is a human phosphoglycerate dehydrogenase inhibitor, cytotoxic to PHGDH-dependent cancer cells.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥267 | 有现货 |
|
| 5MG | ￥421 | 有现货 |
|
| 10MG | ￥640 | 有现货 |
|
| 25MG | ￥1312 | 有现货 |
|
| 50MG | ￥2049 | 有现货 |
|
| 100MG | ￥3540 | 有现货 |
|
| 500MG | ￥7954 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称NCT-502
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述NCT-502 is a human phosphoglycerate dehydrogenase inhibitor, cytotoxic to PHGDH-dependent cancer cells.
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产品描述NCT-502 is a human phosphoglycerate dehydrogenase inhibitor, cytotoxic to PHGDH-dependent cancer cells. It decreases glucose-derived serine production and it has an IC50 of 3.7 μM against PHGDH.(In Vitro):NCT-502 is cytotoxic to MDA-MB-468 (EC50: 15.2 μM).
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同义词N-(4,6-dimethylpyridin-2-yl)-4-[5-(trifluoromethyl)pyridin-2-yl]piperazine-1-carbothioamide
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通路Metabolic Enzyme/Protease
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靶点Dehydrogenase
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受体Crimean-Congo hemorrhagic fever virus (CCHFV); Nucleoside Antimetabolite/Analog
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研究领域——
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适应症——
化学信息
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CAS Number1542213-00-2
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分子量395.5
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分子式C18H20F3N5S
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纯度>98% (HPLC)
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溶解度——
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SMILESCc1cc(C)nc(NC(=S)N2CCN(CC2)c2ccc(cn2)C(F)(F)F)c1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Stephen R Welch, et al. Identification of 2'-deoxy-2'-fluorocytidine as a potent inhibitor of Crimean-Congo hemorrhagic fever virus replication using a recombinant fluorescent reporter virus. Antiviral Res. 2017 Nov;147:91-99.
产品手册
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