021-51111890
购物车（）
sales@molnova.cn
NCT-502
CAS No. 1542213-00-2
NCT-502 ( N-(4,6-dimethylpyridin-2-yl)-4-[5-(trifluoromethyl)pyridin-2-yl]piperazine-1-carbothioamide )
产品货号. M26771 CAS No. 1542213-00-2
NCT-502 is a human phosphoglycerate dehydrogenase inhibitor, cytotoxic to PHGDH-dependent cancer cells.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥267 | 有现货 |
|
| 5MG | ￥421 | 有现货 |
|
| 10MG | ￥640 | 有现货 |
|
| 25MG | ￥1312 | 有现货 |
|
| 50MG | ￥2049 | 有现货 |
|
| 100MG | ￥3540 | 有现货 |
|
| 500MG | ￥7954 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称NCT-502
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述NCT-502 is a human phosphoglycerate dehydrogenase inhibitor, cytotoxic to PHGDH-dependent cancer cells.
-
产品描述NCT-502 is a human phosphoglycerate dehydrogenase inhibitor, cytotoxic to PHGDH-dependent cancer cells. It decreases glucose-derived serine production and it has an IC50 of 3.7 μM against PHGDH.(In Vitro):NCT-502 is cytotoxic to MDA-MB-468 (EC50: 15.2 μM).
-
同义词N-(4,6-dimethylpyridin-2-yl)-4-[5-(trifluoromethyl)pyridin-2-yl]piperazine-1-carbothioamide
-
通路Metabolic Enzyme/Protease
-
靶点Dehydrogenase
-
受体Crimean-Congo hemorrhagic fever virus (CCHFV); Nucleoside Antimetabolite/Analog
-
研究领域——
-
适应症——
化学信息
-
CAS Number1542213-00-2
-
分子量395.5
-
分子式C18H20F3N5S
-
纯度>98% (HPLC)
-
溶解度——
-
SMILESCc1cc(C)nc(NC(=S)N2CCN(CC2)c2ccc(cn2)C(F)(F)F)c1
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1.Stephen R Welch, et al. Identification of 2'-deoxy-2'-fluorocytidine as a potent inhibitor of Crimean-Congo hemorrhagic fever virus replication using a recombinant fluorescent reporter virus. Antiviral Res. 2017 Nov;147:91-99.
产品手册
关联产品
-
Bavachinin
Bavachinin(7-O-Methylbavachin) is a natural compound isolated from the Chinese herb Fructus Psoraleae with potent anti-angiogenic activity.
-
AVN944
AVN-944(VX-944) is a selective, noncompetitive inhibitor of the enzyme directed against human IMPDH with Ki of 6-10 nM for IMPDH1/IMPDH2.
-
hDHODH-IN-5
hDHODH-IN-5 is an inhibitor of human dihydroorotate dehydrogenase.
