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ML-097

CAS No. 743456-83-9

ML-097 ( —— )

产品货号. M27490 CAS No. 743456-83-9

ML-097 (CID-2160985) 是 Ras 相关 GTP 酶的泛激活剂。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥478 有现货
10MG ¥705 有现货
25MG ¥1158 有现货
50MG ¥1725 有现货
100MG ¥2576 有现货
500MG ¥6180 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    ML-097
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    ML-097 (CID-2160985) 是 Ras 相关 GTP 酶的泛激活剂。
  • 产品描述
    ML-097 (CID-2160985) is a pan activator of Ras-related GTPases.(In Vitro):Activators of Cdc42 function might have a beneficial function in solid tumors and ameliorate faciogenital dysplasia where Cdc42 GEF is mutant. Rho GTPases affect cell proliferation and migration . In some cases underexpression is associated with cancer.(In Vivo):Rac2 is selectively expressed in immune cells and human Rac2 mutations result in immunodeficiency. Therefore, activators of Rac2 or other Rac family members might be of benefit in these diseases. Rac1 is important for maintaining hair follicle integrity and a rac1 deficiency in the skin causes nearly complete hair loss in an animal model.
  • 体外实验
    ML-099 activates cell division cycle 42 activated mutant, cell division cycle 42 wild type, Ras protein wild type, GTP-binding protein (Rab7), Rac1 protein activated mutant, Rac1 protein wild type, and Ras protein activated mutant with EC50 values of 50.11 nM, 102.32 nM, 109.64 nM, 20.41 nM, 81.28 nM, 151.35 nM, and 93.32 nM, respectively.
  • 体内实验
    ——
  • 同义词
    ——
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    IL-6|SARS-CoV
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    743456-83-9
  • 分子量
    307.143
  • 分子式
    C14H11BrO3
  • 纯度
    >98% (HPLC)
  • 溶解度
    In Vitro:?DMSO : 100 mg/mL (325.58 mM)
  • SMILES
    OC(=O)c1ccccc1OCc1ccccc1Br
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Xiaoyun Shu, et al. Bioassay-guided separation of the proinflammatory constituents from the roots of Euphorbia kansui. J Nat Med. 2010 Jan;64(1):98-103.
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