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Ranolazine
CAS No. 95635-55-5
Ranolazine ( CVT 303 | RS 43285-003 )
产品货号. M19284 CAS No. 95635-55-5
雷诺嗪是一种通过钠/钙通道的钙摄取抑制剂,用于治疗慢性心绞痛。
纯度: >98% (HPLC)
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规格 | 价格/人民币 | 库存 | 数量 |
50MG | ¥462 | 有现货 |
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100MG | ¥656 | 有现货 |
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200MG | ¥1013 | 有现货 |
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500MG | ¥1717 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Ranolazine
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述雷诺嗪是一种通过钠/钙通道的钙摄取抑制剂,用于治疗慢性心绞痛。
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产品描述Ranolazine is a calcium uptake inhibitor via the sodium/calcium channel, used to treat chronic angina. It affects the sodium-dependent calcium channels during myocardial ischemia in rabbits by altering the intracellular sodium level.(In Vivo):Ranolazine (Bolus injection 10 mg/kg and infusion 9.6 mg/kg/h; bolus injection; for 145 minutes; male Wistar rats) treatment significantly reduces infarct size and cardiac troponin T release in rats subjected to left anterior descending coronary artery occlusion-reperfusion.
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体外实验——
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体内实验Ranolazine (Bolus injection 10 mg/kg and infusion 9.6 mg/kg/h; bolus injection; for 145 minutes; male Wistar rats) treatment significantly reduces infarct size and cardiac troponin T release in rats subjected to left anterior descending coronary artery occlusion-reperfusion. Animal Model:Male Wistar rats (240-350 g) Dosage:Bolus injection 10 mg/kg and infusion (9.6 mg/kg/h) Administration:Bolus injection; for 145 minutes Result: Significantly reduced infarct size and cardiac troponin T release in rats subjected to left anterior descending coronary artery occlusion-reperfusion.
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同义词CVT 303 | RS 43285-003
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通路Others
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靶点Other Targets
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受体Calcium Channel
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研究领域Cardiovascular Disease
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适应症——
化学信息
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CAS Number95635-55-5
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分子量427.54
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分子式C24H33N3O4
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纯度>98% (HPLC)
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溶解度DMSO : 125 mg/mL 292.37 mM
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SMILESCOc1ccccc1OCC(O)CN1CCN(CC(=O)Nc2c(C)cccc2C)CC1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Undrovinas AI, et al. J Cardiovasc Electrophysiol,2006, 17 Suppl 1, S169-S177.
产品手册
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