IDE1 ( IDE1; IDE-1; IDE 1 )

产品货号. M17158 CAS No. 1160927-48-9

COA

Datasheet

HNMR

HPLC

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产品名称

IDE1
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

IDE1 can induce definitive endoderm from embryonic stem cells. It has been shown to induce the differentiation of Sox17+/FoxA2+-expressing pancreatic progenitors from human and mouse embryonic stems cells.
产品描述

IDE1 is a potent cell-permeable definitive endoderm formation inducer (EC50 = 125 nM, ESC) similar to IDE 2 (ab145223). IDE1 induces Sox17 expression. It also activates TGF-β signaling and downstream Smad2 phosphorylation. IDE1 upregulates Nodal expression.
同义词

IDE1; IDE-1; IDE 1
通路

Others
靶点

Other Targets
受体

Others
研究领域

Inflammation/Immunology
适应症

——

1. Hoveizi E, et al. J Biomed Mater Res A. 2014 Nov;102(11):4027-36.

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