4-tert-Octylphenol

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

4-tert-Octylphenol 是一种干扰内分泌的化学物质，是一种雌激素活性分子。4-tert-Octylphenol 诱导子代小鼠脑神经元祖细胞凋亡。4-tert-Octylphenol 减少溴脱氧尿苷 (BrdU)、有丝分裂标志物 Ki67 和磷酸组蛋白 H3 (p-Histone-H3)，从而导致神经元祖细胞增殖减少。4-tert-Octylphenol 会破坏小鼠的大脑发育和行为。

4-tert-Octylphenol, a endocrine-disrupting chemical, is an estrogenic agent. 4-tert-Octylphenol induces apoptosis in neuronal progenitor cells in offspring mouse brain. 4-tert-Octylphenol reduces bromodeoxyuridine (BrdU), mitotic marker Ki67, and phospho-histone H3 (p-Histone-H3), resulting in a reduction of neuronal progenitor proliferation. 4-tert-Octylphenol disrupts brain development and behavior in mice.

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Proteasome/Ubiquitin

Endogenous Metabolite

Endogenous Metabolite

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140-66-9

206.32

C14H22O

>98% (HPLC)

In Vitro:?DMSO 中的溶解度 : 100 mg/mL (484.68 mM; 超声助溶 )

CC(C)(C)CC(C)(C)C1=CC=C(O)C=C1

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(-20℃)

With Ice Pack

≥ 2 years