Vasopressin

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Vasopressin 是一种环状九肽，在下丘脑中枢合成。Vasopressin 参与下丘脑-垂体-肾上腺轴，并通过增强促肾上腺皮质激素释放因子的刺激作用调节垂体促肾上腺皮质激素分泌。Vasopressin 也可以作为一种神经递质，通过与特定的 G 蛋白偶联受体结合来发挥其作用。

Vasopressin is a cyclic nonapeptide that is synthesized centrally in the hypothalamus. Vasopressin participates in the hypothalamic-pituitary-adrenal axis, and regulates pituitary corticotropin secretion by potentiating the stimulatory effects of corticotropin releasing factor. Vasopressin also can act as a neurotransmitter, exerting its action by binding to specific G protein-coupled receptors.

AVP (0.01 nM-1 μM) induces Ca2+ increase in Chinese hamster ovary cells expressing rat or human V1b receptors.

Vasopressin (0.03-0.3μg/kg; i.p.) potentiates corticotropin release provoked by exogenous corticoliberin and increases corticotropin secretion subsequent to body water loss.Vasopressin (0.001-0.1?mg/kg; i.p.) potently increases adjacent lying, where rats meeting for the first time lie passively next to each other.

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Proteasome/Ubiquitin

Endogenous Metabolite

Endogenous Metabolite

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11000-17-2

1084.24

C46H65N15O12S2

>98% (HPLC)

In Vitro:?DMSO 中的溶解度 : 100 mg/mL (92.23 mM; 超声助溶 ) H2O 中的溶解度 : 50 mg/mL (46.12 mM; 超声助溶)

O=C([C@@H](N)CSSC[C@H](NC1=O)C(N2[C@H](C(N[C@H](C(NCC(N)=O)=O)CCCNC(N)=N)=O)CCC2)=O)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H]1CC(N)=O)=O)CCC(N)=O)=O)CC3=CC=CC=C3)=O)CC4=CC=C(O)C=C4

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(-20℃)

With Ice Pack

≥ 2 years