N6-Isopentenyladenosine

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

N6-异戊烯基腺苷是甲羟戊酸途径的终产物，是一种具有抗黑色素瘤活性的自噬抑制剂。 N6-异戊烯基腺苷是细胞分裂素中发现的一种 RNA 修饰，可调节植物生长/分化并提高效率。

N6-Isopentenyladenosine, an end product of the mevalonate pathway, is an autophagy inhibitor with anti-melanoma activity. N6-Isopentenyladenosine, an RNA modification found in cytokinins, regulates plant growth/differentiation and improves the efficiency (In Vitro):N6-Isopentenyladenosine targets both AMPK and Rab7 prenylation and inhibits melanoma growth through the impairment of autophagic flux.

N6-isopentenyladenosine dual targeting of AMPK and Rab7 prenylation inhibits melanoma growth through the impairment of autophagic flux.

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Proteasome/Ubiquitin

Endogenous Metabolite

Tankyrase

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7724-76-7

335.364

C15H21N5O4

>98% (HPLC)

In Vitro:?DMSO : 100 mg/mL (298.19 mM)

CC(C)=CCNc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O

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(-20℃)

With Ice Pack

≥ 2 years