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L-Phenylalanine-15N

CAS No. 29700-34-3

L-Phenylalanine-15N ( (S)-2-Amino-3-phenylpropionic acid-15N )

产品货号. M28293 CAS No. 29700-34-3

L-苯丙氨酸-15N ((S)-2-氨基-3-苯基丙酸-15N) 是 15N 标记的 L-苯丙氨酸。 L-苯丙氨酸((S)-2-氨基-3-苯基丙酸)是从大肠杆菌中分离出来的必需氨基酸。 L-苯丙氨酸是电压依赖性 Ca + 通道拮抗剂的 α2δ 亚基,K i 为 980 nM。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥211 有现货
10MG ¥330 有现货
25MG ¥524 有现货
50MG ¥769 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    L-Phenylalanine-15N
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    L-苯丙氨酸-15N ((S)-2-氨基-3-苯基丙酸-15N) 是 15N 标记的 L-苯丙氨酸。 L-苯丙氨酸((S)-2-氨基-3-苯基丙酸)是从大肠杆菌中分离出来的必需氨基酸。 L-苯丙氨酸是电压依赖性 Ca + 通道拮抗剂的 α2δ 亚基,K i 为 980 nM。
  • 产品描述
    L-Phenylalanine-15N ((S)-2-Amino-3-phenylpropionic acid-15N) is the 15N-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli . L-Phenylalanine is a α2δ subunit of voltage-dependent Ca + channels antagonist with a K i of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) ( K B of 573 μM ) and non-NMDARs , respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals .(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs .
  • 体外实验
    Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
  • 体内实验
    ——
  • 同义词
    (S)-2-Amino-3-phenylpropionic acid-15N
  • 通路
    GPCR/G Protein
  • 靶点
    Calcium Channel
  • 受体
    TNF-α|PPARγ|inflammation|IL-12|IL-6
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    29700-34-3
  • 分子量
    166.18
  • 分子式
    C9H11NO2
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    [15NH2][C@@H](CC1=CC=CC=C1)C(O)=O
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Quang TH, et al. Inhibitory effects of oleanane-type triterpenes and saponins from the stem bark of Kalopanax pictus on LPS-stimulated pro-inflammatory cytokine production in bone marrow-derived dendritic cells. Arch Pharm Res. 2013 Mar;36(3):327-34.
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