L-Phenylalanine-15N
CAS No. 29700-34-3
L-Phenylalanine-15N ( (S)-2-Amino-3-phenylpropionic acid-15N )
产品货号. M28293 CAS No. 29700-34-3
L-苯丙氨酸-15N ((S)-2-氨基-3-苯基丙酸-15N) 是 15N 标记的 L-苯丙氨酸。 L-苯丙氨酸((S)-2-氨基-3-苯基丙酸)是从大肠杆菌中分离出来的必需氨基酸。 L-苯丙氨酸是电压依赖性 Ca + 通道拮抗剂的 α2δ 亚基,K i 为 980 nM。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ¥211 | 有现货 |
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| 10MG | ¥330 | 有现货 |
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| 25MG | ¥524 | 有现货 |
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| 50MG | ¥769 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
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| 1G | 获取报价 | 有现货 |
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生物学信息
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产品名称L-Phenylalanine-15N
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述L-苯丙氨酸-15N ((S)-2-氨基-3-苯基丙酸-15N) 是 15N 标记的 L-苯丙氨酸。 L-苯丙氨酸((S)-2-氨基-3-苯基丙酸)是从大肠杆菌中分离出来的必需氨基酸。 L-苯丙氨酸是电压依赖性 Ca + 通道拮抗剂的 α2δ 亚基,K i 为 980 nM。
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产品描述L-Phenylalanine-15N ((S)-2-Amino-3-phenylpropionic acid-15N) is the 15N-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli . L-Phenylalanine is a α2δ subunit of voltage-dependent Ca + channels antagonist with a K i of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) ( K B of 573 μM ) and non-NMDARs , respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals .(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs .
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体外实验Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
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体内实验——
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同义词(S)-2-Amino-3-phenylpropionic acid-15N
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通路GPCR/G Protein
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靶点Calcium Channel
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受体TNF-α|PPARγ|inflammation|IL-12|IL-6
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研究领域——
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适应症——
化学信息
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CAS Number29700-34-3
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分子量166.18
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分子式C9H11NO2
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纯度>98% (HPLC)
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溶解度——
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SMILES[15NH2][C@@H](CC1=CC=CC=C1)C(O)=O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Quang TH, et al. Inhibitory effects of oleanane-type triterpenes and saponins from the stem bark of Kalopanax pictus on LPS-stimulated pro-inflammatory cytokine production in bone marrow-derived dendritic cells. Arch Pharm Res. 2013 Mar;36(3):327-34.
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