Indobufen

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Indobufen 是一种血小板聚集抑制剂，是一种可逆性血小板环氧合酶 (Cox) 活性抑制剂。吲哚布芬抑制血栓素 A2 (TxA2) 的合成。 Indobufen 下调单核细胞中的组织因子 (TF)。

Indobufen is an inhibitor of platelet aggregation and is a reversible platelet cyclooxygenase (Cox) activity inhibitor. Indobufen suppresses thromboxane A2 (TxA2) synthesis. Indobufen down-regulates tissue factor (TF) in monocytes.(In Vitro):Indobufen suppresses TxA2 but not PGE2 synthesis in LPS-stimulated monocytes. Indobufen causes the extent of ERK1/2 phosphorylation, whereas the levels of phosphorylated p38 are unaltered. Indobufen does not affect both Cox-1 and Cox-2 protein, whereas Indobufen reduces TxB2 levels.

Indobufen does not affect both Cox-1 and Cox-2 protein, whereas Indobufen reduces TxB2 levels. Indobufen inhibits TxA2 but not PGE2 synthesis in LPS-stimulated monocytes. Indobufen reduces the extent of ERK1/2 phosphorylation, whereas the levels of phosphorylated p38 are unaltered.

——

Ibustrin

Chromatin/Epigenetic

COX

RSV

——

——

63610-08-2

295.338

C18H17NO3

>98% (HPLC)

In Vitro:?DMSO : 250 mg/mL (846.51 mM)

CCC(C(O)=O)c1ccc(cc1)N1Cc2ccccc2C1=O

——

(-20℃)

With Ice Pack

≥ 2 years