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Arimoclomol
CAS No. 289893-25-0
Arimoclomol ( BRX-220 free base )
产品货号. M26548 CAS No. 289893-25-0
Arimoclomol 是热休克蛋白 (HSP) 的共同诱导剂，可用于治疗肌萎缩侧索硬化症 (ALS) 的研究。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥847 | 有现货 |
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| 10MG | ￥1378 | 有现货 |
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| 25MG | ￥2288 | 有现货 |
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| 50MG | ￥3376 | 有现货 |
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| 100MG | ￥4653 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥905 | 有现货 |
|
生物学信息
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产品名称Arimoclomol
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Arimoclomol 是热休克蛋白 (HSP) 的共同诱导剂，可用于治疗肌萎缩侧索硬化症 (ALS) 的研究。
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产品描述Arimoclomol is a co-inducer of heat shock proteins (HSP) and can be used in studies about the treatment of amyotrophic lateral sclerosis (ALS).(In Vivo):In male Wistar rats, Arimoclomol (20 mg/kg; gavage) protects cholecystokinin-octapeptide (CCK)-induced acute pancreatitis. The pancreatic levels of HSP60 and HSP72 are significantly increased.
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体外实验——
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体内实验Arimoclomol (BRX-220; 20 mg/kg; orally administered for 5 d) has a protective effect againstcholecystokinin-octapeptide (CCK)-induced acute pancreatitis. Animal Model:Male Wistar rats weighing 240 to 270 gDosage:20 mg/kg Administration:Administered intragastrically, for 5 daysResult:Had a protective effect against CCK-induced acute pancreatitis.
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同义词BRX-220 free base
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通路Cytoskeleton/Cell Adhesion Molecules
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靶点HSP
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受体AP-1| LOX| NF-κB| Parasite
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研究领域——
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适应症——
化学信息
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CAS Number289893-25-0
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分子量313.78
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分子式C14H20ClN3O3
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纯度>98% (HPLC)
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溶解度——
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SMILESO[C@@H](CO\N=C(/Cl)c1cccn(=O)c1)CN1CCCCC1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Hadjipavlou-Litina D, et al. Kukoamine A analogs with lipoxygenase inhibitory activity. J Enzyme Inhib Med Chem. 2009 Oct;24(5):1188-93.
