Lynestrenol

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Lynestrenol 是一种合成的孕激素，是黄体酮受体激动剂。

Lynestrenol is a synthetic progestational hormone is the progesterone receptor?agonist.(In Vitro):Lynestrenol markedly enhances the lymphocyte response to phytohemagglutinin, the mixed lymphocyte culture, the active T-rosette test, the autologous red cell rosettes, and the number of nonadherent cells in the leukocyte adherence inhibition test. Lynestrenol also increases monocyte phagocytosis. Lynestrenol delays the appearance of malignant tumors in hamsters.(In Vivo):Lynestrenol has both a genotoxic and cytotoxic effects in mouse bone marrow cells. Lynestrenol is studied at three different doses (6.87, 13.75 and 27.50 mg/kg). Sister chromatid exchanges (SCEs) and chromosomal aberrations (CAs) increase significantly as compared to normal control when treated with Lynestrenol at 13.75 and 27.50 mg/kg.

Lynestrenol markedly enhances the lymphocyte response to phytohemagglutinin, the mixed lymphocyte culture, the active T-rosette test, the autologous red cell rosettes, and the number of nonadherent cells in the leukocyte adherence inhibition test. Lynestrenol also increases monocyte phagocytosis. Lynestrenol delays the appearance of malignant tumors in hamsters.

Lynestrenol has both a genotoxic and cytotoxic effects in mouse bone marrow cells. Lynestrenol is studied at three different doses (6.87, 13.75 and 27.50 mg/kg). Sister chromatid exchanges (SCEs) and chromosomal aberrations (CAs) increase significantly as compared to normal control when treated with Lynestrenol at 13.75 and 27.50 mg/kg.

——

Endocrinology/Hormones

Estrogen Receptor/ERR

progesterone receptor

Neurological Disease

Transsexualism and Gender Dysphoria.

52-76-6

284.4

C20H28O

>98% (HPLC)

DMSO:56 mg/mL (196.87 mM)

[H][C@@]12CC[C@@](O)(C#C)[C@@]1(C)CC[C@]1([H])[C@@]3([H])CCCC=C3CC[C@@]21[H]

19 Norpregn-4-en-20-yn-17-ol (17alpha)-

(-20℃)

With Ice Pack

≥ 2 years