Levomefolic Acid

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

左甲亚叶酸是叶酸的一种天然活性形式，在细胞水平上用于 DNA 复制、半胱氨酸循环和同型半胱氨酸的调节等功能。左甲亚叶酸用于治疗和预防叶酸缺乏症。

Levomefolinic acid is a natural active form of folic acid used at the cellular level for DNA reproduction the cysteine cycle and the regulation of homocysteine among other functions.?Levomefolinic acid is used as a treatment and to prevent Folate Deficiency.(In Vitro):Levomefolic acid (5-MTHF) shows interaction with residues Glu406, Ile 418, Lys417 and Tyr453, of which Lys 417 and Tyr 453 play a strong physiological role in the interaction between S1 and ACE and may act as a potential inhibitor of the S1:ACE2 interaction of the SARS-CoV-2 virus.Levomefolic acid (5-MTHF) (50 nM, 72 h) increases intracellular folate metabolite activity by 7-fold better than folic acid by 2-fold in human lymphoblastoid cell line (LCL), and is a good folic acid supplement.

Levomefolic acid (5-MTHF) shows interaction with residues Glu406, Ile 418, Lys417 and Tyr453, of which Lys 417 and Tyr 453 play a strong physiological role in the interaction between S1 and ACE and may act as a potential inhibitor of the S1:ACE2 interaction of the SARS-CoV-2 virus.Levomefolic acid (5-MTHF) (50 nM, 72 h) increases intracellular folate metabolite activity by 7-fold better than folic acid by 2-fold in human lymphoblastoid cell line (LCL), and is a good folic acid supplement.

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5-MTHF

Proteasome/Ubiquitin

Endogenous Metabolite

Human Endogenous Metabolite

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31690-09-2

459.46

C20H25N7O6

>98% (HPLC)

H2O:5 mg/mL (10.88 mM);DMSO:0.526 mg/mL (1.14 mM)

CN1[C@@H](CNc2ccc(cc2)C(=O)N[C@@H](CCC(O)=O)C(O)=O)CNc2nc(N)[nH]c(=O)c12

(4-((((S)-2-amino-5-methyl-4-oxo-145678-hexahydropteridin-6-yl)methyl)amino)benzoyl)-L-glutamic acid

(-20℃)

With Ice Pack

≥ 2 years