Amikacin disulfate

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

阿米卡星硫酸盐（BAY416651硫酸盐）是一种源自卡那霉素A的半合成氨基糖苷类抗生素。

Amikacin sulfate(BAY416651 sulfate) is a semi-synthetic aminoglycoside antibiotic derived from kanamycin A.(In Vitro):Amikacin offers definite advantages for treating infections caused by organisms resistant to other aminoglycosides. Amikaci is affected by relatively few arninoglycoside-modifying enzymes. Amikacin is useful in the treatment of infections caused by Nocardia asteroides, Mycobacterium avium-intracellulare, and certain species of "rapid-growing" mycobacteria (that is, M. chelonae and M. fortuitumi).Amikacin (100-1500 μM) causes a reliable dose-dependent loss of lateral line zebrafish hair cells with a LD50 value of 453 μM.(In Vivo):Amikacin (320?mg/kg; subcutaneous injection; daily; for 10 days; male Fischer rats) treatment increases the chance of serious hearing loss in rats in vivo.

Amikacin offers definite advantages for treating infections caused by organisms resistant to other aminoglycosides. Amikaci is affected by relatively few arninoglycoside-modifying enzymes. Amikacin is useful in the treatment of infections caused by Nocardia asteroides, Mycobacterium avium-intracellulare, and certain species of "rapid-growing" mycobacteria (that is, M. chelonae and M. fortuitumi).Amikacin (100-1500 μM) causes a reliable dose-dependent loss of lateral line zebrafish hair cells with a LD50 value of 453 μM.

Amikacin (320mg/kg; subcutaneous injection; daily; for 10 days; male Fischer rats) treatment increases the chance of serious hearing loss in rats in vivo. Animal Model:Male Fischer 344 rats (40-50-day-old) Dosage:320?mg/kg Administration:Subcutaneous injection; daily; for 10 days Result:Induced hearing loss in rats.

BAY-416651 sulfate

Endocrinology/Hormones

5-HT Receptor

16S rRNA

Infection

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39831-55-5

781.76

C22H43N5O13·2H2O4S

>98% (HPLC)

H2O : ≥ 50 mg/mL; 63.96 mM

OS(O)(=O)=O.OS(O)(=O)=O.NCC[C@H](O)C(=O)N[C@@H]1C[C@H](N)[C@@H](O[C@H]2O[C@H](CN)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O[C@H]1O[C@H](CO)[C@@H](O)[C@H](N)[C@H]1O

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(-20℃)

With Ice Pack

≥ 2 years