Levonorgestrel

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

左炔诺孕酮是一种合成孕激素，用作某些激素避孕药的活性成分。

Levonorgestrel is a synthetic progestogen used as an active ingredient in some hormonal contraceptives.

Western Blot Analysis Cell Line:Uterine leiomyoma cells Concentration:5 mg/mL; 10mg/mL; 20 mg/mL Incubation Time:Result:Inhibited Bcl-2 and survivin expression at high concentrations (10 mg/mL and 20 mg/mL). Significantly increased the phosphorylation of P38 phosphorylation and increased Caspase-3 expression at high concentrations (10 mg/mL and 20 mg/mL).

Animal Model:Apodemus agrarius modelDosage:1 mg/kg Administration:Intragastric administration (i.g.), Once daily for three days Result:Damaged the sperm ducts, reduced sperm production in combination with quinestrol.Reduced population density in the field in combination with quinestrol.

Levonorgestrel, Norgestrel, Microval, Postinor, Mirena, Plan B

Endocrinology/Hormones

Estrogen Receptor/ERR

ER| SRD5A1

Endocrinology

——

797-63-7

312.45

C21H28O2

>98% (HPLC)

Ethanol: 2 mg/mL (6.4 mM); DMSO: 45 mg/mL (144.02 mM)

CC[C@]12CC[C@H]3[C@@H](CCC4=CC(CC[C@H]34)=O)[C@@H]1CC[C@@]2(O)C#C

(8R,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-17-hydroxy-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one

(-20℃)

With Ice Pack

≥ 2 years