Mefenamic acid

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

甲芬那酸是一种非甾体抗炎药。甲芬那酸的作用机制是作为环加氧酶抑制剂。

Mefenamic acid is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of mefenamic acid is as a Cyclooxygenase Inhibitor. The chemical classification of mefenamic acid is Nonsteroidal Anti-inflammatory Compounds.(In Vitro):Mefenamic acid is a non-steroidal anti-inflammatory agent, acting as a competitive inhibitor of hCOX-1, with IC50s of 40 nM and 3 μM for hCOX-1 and hCOX-2, respectively. Mefenamic acid (0-100 μM) has cytotoxic effects on KB, Saos-2, and 1321N cells, however, U-87MG cells are resistant to Mefenamic acid.

Mefenamic acid is a non-steroidal anti-inflammatory agent, acting as a competitive inhibitor of hCOX-1, with IC50s of 40 nM and 3 μM for hCOX-1 and hCOX-2, respectively. Mefenamic acid (0-100 μM) has cytotoxic effects on KB, Saos-2, and 1321N cells, however, U-87MG cells are resistant to Mefenamic acid.

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C.I. 473 | NSC 94437

Chromatin/Epigenetic

COX

COX-1| COX-2

Inflammation/Immunology

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61-68-7

241.29

C15H15NO2

>98% (HPLC)

DMSO: 48 mg/mL (198.93 mM)

c1(c(cccc1)C(=O)O)Nc1c(c(ccc1)C)C

2-(2,3-dimethylanilino)benzoic acid

(-20℃)

With Ice Pack

≥ 2 years