Bengenin
CAS No. 477-90-7
Bengenin ( (–)-Bergenin | Cuscutin | NSC 661749 )
产品货号. M14593 CAS No. 477-90-7
岩白菜素是一种多酚,是一种具有抗氧化作用的有效抗麻醉剂。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 50MG | ¥140 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
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| 1G | 获取报价 | 有现货 |
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| 1 mL x 10 mM in DMSO | ¥124 | 有现货 |
|
生物学信息
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产品名称Bengenin
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述岩白菜素是一种多酚,是一种具有抗氧化作用的有效抗麻醉剂。
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产品描述Bergenin, a polyphenol, is a potent antinarcotic agent with antioxidant action. (In Vitro):Bergenin (7.5-30μM; 24 hours) decreases the viability of HeLa cervical cancer cells (IC50=15 μM).Bergenin (7.5-30 μM; 24 hours) induces apoptosis in HeLa cervical cancer cells.(In Vivo):Pretreatment with Bergenin (12.5-100 mg/kg; i.p.; once) produces a dose-related inhibition of acetic acid-induced writhing in mice.
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体外实验Bergenin (7.5-30μM; 24 hours) decreases the viability of HeLa cervical cancer cells (IC50=15 μM).Bergenin (7.5-30 μM; 24 hours) induces apoptosis in HeLa cervical cancer cells. Cell Viability Assay Cell Line:HeLa cervical cancer cells Concentration:7.5, 15, 30 μM Incubation Time:24 hours Result:Decreased the viability of HeLa cervical cancer cells.Cell Viability Assay Cell Line:HeLa cervical cancer cells Concentration:7.5, 15, 30 μM Incubation Time:24 hours Result:Induced apoptosis in HeLa cervical cancer cells.
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体内实验Pretreatment with Bergenin (12.5-100 mg/kg; i.p.; once) produces a dose-related inhibition of acetic acid-induced writhing in mice. Animal Model:Male Swiss Webster C57BL/6 mice Dosage:12.5, 25, 50, 100 mg/kg Administration:i.p.; Once Result:Produced a dose-related inhibition of acetic acid-induced writhing in mice.
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同义词(–)-Bergenin | Cuscutin | NSC 661749
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通路Apoptosis
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靶点IL Receptor
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受体IL-1β| IL-6| NF-κB| NOD| TNF-α
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研究领域Other Indications
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适应症——
化学信息
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CAS Number477-90-7
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分子量328.27
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分子式C14H16O9
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纯度>98% (HPLC)
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溶解度DMSO: 66 mg/mL (201.05 mM)
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SMILESCOC1=C(C=C2C(=C1O)[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)OC2=O)O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Gao XJ, et al. Inflammation. 2015 Jun;38(3):1142-50.
产品手册
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