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BMS-394136
CAS No. 343246-73-1
BMS-394136 ( BMS394136 )
产品货号. M14168 CAS No. 343246-73-1
BMS-394136 是一种有效的选择性 IKur/Kv1.5 抑制剂。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥4304 | 有现货 |
|
| 10MG | ￥6147 | 有现货 |
|
| 25MG | ￥9049 | 有现货 |
|
| 50MG | ￥11997 | 有现货 |
|
| 100MG | ￥15930 | 有现货 |
|
| 500MG | ￥31770 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称BMS-394136
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述BMS-394136 是一种有效的选择性 IKur/Kv1.5 抑制剂。
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产品描述BMS-394136 is a potent, selective IKur/Kv1.5inhibitor, increases atrial action potential duration (APD) and prolongs AERP but not VERP in both rabbits and beagles.Heart Arrhythmia Phase 1 Discontinued.
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体外实验——
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体内实验——
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同义词BMS394136
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通路Cell Cycle/DNA Damage
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靶点Potassium Channel
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受体Potassium Channel
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研究领域Cardiovascular Disease
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适应症Heart Arrhythmia
化学信息
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CAS Number343246-73-1
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分子量471.357
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分子式C24H21Cl2FN4O
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纯度>98% (HPLC)
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溶解度——
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SMILESCC1=C([C@H](n2c(ccn2)N1)c3ccc(c(c3)Cl)Cl)C(=O)N4CCC[C@H]4c5ccc(cc5)F
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化学全称Pyrrolidine, 1-[[(7R)-7-(3,4-dichlorophenyl)-4,7-dihydro-5-methylpyrazolo[1,5-a]pyrimidin-6-yl]carbonyl]-2-(4-fluorophenyl)-, (2S)- (9CI)
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Dezhi Xing, et al. Abstract 2515: A Selective IKur Blocker, BMS-394136 Selectively Prolongs Atrial APD and Refractoriness in Beagles and Rabbits. Circulation. 2009;120:S654.
产品手册
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