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Diethylcarbamazine citrate
CAS No. 1642-54-2
Diethylcarbamazine citrate ( Diethylcarbamazine citrate )
产品货号. M12496 CAS No. 1642-54-2
Diethcarbamazine citrate 是丝虫微丝蚴中花生四烯酸代谢的抑制剂；对多种寄生虫具有高度特异性，并且不含任何有毒金属元素。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 25MG | ￥124 | 有现货 |
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| 50MG | ￥161 | 有现货 |
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| 100MG | ￥260 | 有现货 |
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| 500MG | ￥596 | 有现货 |
|
| 1G | ￥876 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥302 | 有现货 |
|
生物学信息
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产品名称Diethylcarbamazine citrate
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Diethcarbamazine citrate 是丝虫微丝蚴中花生四烯酸代谢的抑制剂；对多种寄生虫具有高度特异性，并且不含任何有毒金属元素。
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产品描述Diethylcarbamazine citrate is an inhibitor of arachidonic acid metabolism in filarial microfilaria; is highly specific for several parasites and does not contain any toxic metallic elements.
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体外实验——
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体内实验Animal Model:HFD-induced obese mice Dosage:50 mg/kg Administration:p.o.Result:Reduced glucose , triglycerides and insulin levels.Reduced the levels of TNF-α, IL-6 and MCP-1.Reduced COX activity and inhibited this translocated or activated NF-κBp65.
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同义词Diethylcarbamazine citrate
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通路Chromatin/Epigenetic
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靶点COX
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受体COX-1| ALOX5
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研究领域Infection
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适应症——
化学信息
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CAS Number1642-54-2
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分子量391.42
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分子式C10H21N3O·C6H8O7
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纯度>98% (HPLC)
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溶解度DMSO: 10 mM
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SMILESO=C(N1CCN(C)CC1)N(CC)CC.OC(C(O)=O)(CC(O)=O)CC(O)=O
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化学全称N,N-diethyl-4-methylpiperazine-1-carboxamide citrate
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Bach MK, Brashler JR. Biochem Pharmacol. 1986 Feb 1;35(3):425-33.
