Mps1-IN-2

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Mps1-IN-2 是一种有效的 Mps1 kianse 抑制剂，IC50 值为 145 nM。

Mps1-IN-2 is a potent Mps1 kianse inhibitor with IC50 value of 145 nM.

Mps1-IN-2 is a potent, selective and ATP-competitive Mps1 kinase inhibitor, with an IC50 and a Kd of 145 nM and 12 nM. Mps1-IN-2 also shows high affinity for PLK1 and GAK with Kds of 61 and 140 nM, respectively, but shows little or no inhibition on other 352 member kinases. Mps1-IN-2 can induces bypass of a checkpoint-mediated mitotic arrest in U2OS cells.

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Cytoskeleton/Cell Adhesion Molecules

Kinesin

Mps1

Cancer

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1228817-38-6

480.6

C26H36N6O3

>98% (HPLC)

DMSO: 10 mM

CCOC1=C(NC2=NC=C3N(C)C(=O)CCN(C4CCCC4)C3=N2)C=CC(=C1)N1CCC(O)CC1

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(-20℃)

With Ice Pack

≥ 2 years