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17-Beta-Estradiol-3,17-Dipropionate

CAS No. 113-38-2

17-Beta-Estradiol-3,17-Dipropionate ( Estradiol dipropionate | Estroici | Estronex | Follicyclin P )

产品货号. M10466 CAS No. 113-38-2

二丙酸雌二醇是天然雌激素雌二醇的合成酯,特别是 3,17-二丙酰酯。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥626 有现货
10MG ¥847 有现货
25MG ¥1330 有现货
50MG ¥2000 有现货
100MG ¥2655 有现货
200MG ¥3861 有现货
500MG 获取报价 有现货
1G 获取报价 有现货
1 mL x 10 mM in DMSO ¥530 有现货

生物学信息

  • 产品名称
    17-Beta-Estradiol-3,17-Dipropionate
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    二丙酸雌二醇是天然雌激素雌二醇的合成酯,特别是 3,17-二丙酰酯。
  • 产品描述
    Estradiol dipropionate is a synthetic ester, specifically the 3,17-dipropanoyl ester, of the natural estrogen, estradiol.(In Vivo):Treatment of Estradiol dipropionate (2μg per 100 g; single subcutaneous injection) and Chorionic gonadotropin (10 IU per 100 g; sc; twice a day) for 2 days, levels of β-catenin and GSK-3β in luminal and glandular epithelia are lower in Ovariectomized mice.Treatment of Estradiol dipropionate (2 μg per 100 g; once a week) and Chorionic gonadotropin ((10 IU per 100 g; once a day) for a month, the incidence of atypical endometrial hyperplasia is significantly higher, the level of β-catenin is slightly higher, and the expression of GSK-3β is lower in luminal and glandular epithelia.
  • 体外实验
    ——
  • 体内实验
    Treatment of Estradiol dipropionate (2μg per 100 g; single subcutaneous injection) and Chorionic gonadotropin (10 IU per 100 g; sc; twice a day) for 2 days, levels of β-catenin and GSK-3β in luminal and glandular epithelia are lower in Ovariectomized mice.Treatment of Estradiol dipropionate (2 μg per 100 g; once a week) and Chorionic gonadotropin ((10 IU per 100 g; once a day) for a month, the incidence of atypical endometrial hyperplasia is significantly higher, the level of β-catenin is slightly higher, and the expression of GSK-3β is lower in luminal and glandular epithelia.
  • 同义词
    Estradiol dipropionate | Estroici | Estronex | Follicyclin P
  • 通路
    Endocrinology/Hormones
  • 靶点
    Estrogen Receptor/ERR
  • 受体
    ER
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    113-38-2
  • 分子量
    384.52
  • 分子式
    C24H32O4
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO: 10 mM
  • SMILES
    C[C@@]12[C@@H](OC(CC)=O)CC[C@@]1([H])[C@]3([H])CCC4=C(C=CC(OC(CC)=O)=C4)[C@@]3([H])CC2
  • 化学全称
    (17beta)-Estra-1,3,5(10)-triene-3,17-diol, dipropanoate

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Noguchi M, et al.J Vet Med Sci. 2013; 75(3):343-8.
产品手册
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