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Lenvatinib
CAS No. 417716-92-8
Lenvatinib ( E7080;E-7080;E 7080 )
产品货号. M14427 CAS No. 417716-92-8
Lenvatinib (E7080) is a multitargeted kinase inhibitor with IC50s of 4/5.2/22/46 nM for VEGFR2/VEGFR3/VEGFR1/FGFR1 in cell free assays.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥340 | 有现货 |
|
| 10MG | ￥470 | 有现货 |
|
| 50MG | ￥996 | 有现货 |
|
| 100MG | ￥1515 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Lenvatinib
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Lenvatinib (E7080) is a multitargeted kinase inhibitor with IC50s of 4/5.2/22/46 nM for VEGFR2/VEGFR3/VEGFR1/FGFR1 in cell free assays.
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产品描述Lenvatinib (E7080) is a multitargeted kinase inhibitor with IC50s of 4/5.2/22/46 nM for VEGFR2/VEGFR3/VEGFR1/FGFR1 in cell free assays; also inhibits PDGFR, Kit with IC50< 100 nM; suppresses the phosphorylation of VEGF receptor-2 and FGF receptor 1 and inhibits proliferation of endothelial cellin vitro; orally active.Kidney Cancer Approved
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同义词E7080;E-7080;E 7080
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通路Angiogenesis
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靶点VEGFR
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受体FGFR1;PDGFRβ;VEGFR1/FLT1;VEGFR2/KDR;VEGFR3/FLT4
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研究领域Cancer
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适应症Kidney Cancer
化学信息
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CAS Number417716-92-8
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分子量426.85
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分子式C21H19ClN4O4
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纯度>98% (HPLC)
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溶解度10 mM in DMSO
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SMILESCOC1=CC2=NC=CC(OC3=CC(Cl)=C(NC(=O)NC4CC4)C=C3)=C2C=C1C(N)=O
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化学全称6-Quinolinecarboxamide, 4-[3-chloro-4-[[(cyclopropylamino)carbonyl]amino]phenoxy]-7-methoxy-
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
2. Matsui J, et al. Clin Cancer Res. 2008 Sep 1;14(17):5459-65.
3. Ikuta K, et al. Clin Cancer Res. 2009 Dec 1;15(23):7229-37.
产品手册
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