021-51111890
购物车（）
sales@molnova.cn
Kif15-IN-1
CAS No. 672926-32-8
Kif15-IN-1 ( KIF15-IN-1; KIF15IN-1; KIF15-IN1; KIF15IN1; KIF15 IN 1 )
产品货号. M15567 CAS No. 672926-32-8
Kif15-IN-1 is a potent, selective inhibitor of KIF15 motility, can act synergistically with Eg5 inhibitors to impair cancer cell proliferation.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥2811 | 有现货 |
|
| 50MG | ￥12069 | 有现货 |
|
| 100MG | ￥16119 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称Kif15-IN-1
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述Kif15-IN-1 is a potent, selective inhibitor of KIF15 motility, can act synergistically with Eg5 inhibitors to impair cancer cell proliferation.
-
产品描述Kif15-IN-1 is a potent, selective inhibitor of KIF15 motility, can act synergistically with Eg5 inhibitors to impair cancer cell proliferation.
-
同义词KIF15-IN-1; KIF15IN-1; KIF15-IN1; KIF15IN1; KIF15 IN 1
-
通路Cytoskeleton/Cell Adhesion Molecules
-
靶点Kinesin
-
受体Kinesin
-
研究领域Cancer
-
适应症——
化学信息
-
CAS Number672926-32-8
-
分子量430.48
-
分子式C20H22N4O5S
-
纯度>98% (HPLC)
-
溶解度DMSO : ≥ 100 mg/mL 232.30 mM; H2O : < 0.1 mg/mL
-
SMILESO=C(C1=C(C)N=C(NC([C@@H](N2C(NC3=C(C=CC=C3)C2=O)=O)C(C)C)=O)S1)OCC
-
化学全称ethyl (S)-2-(2-(2,4-dioxo-1,4-dihydroquinazolin-3(2H)-yl)-3-methylbutanamido)-4-methylthiazole-5-carboxylate
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1. Preparation of quinazolinediones as Kif15 kinesin inhibitors for treating cellular proliferative disorders. Pat. Appl. Publ. (2004), US 20040053948 A1 20040318.
2. Milic B, et al. Proc Natl Acad Sci U S A. 2018 Apr 27. pii: 201801242.
2. Milic B, et al. Proc Natl Acad Sci U S A. 2018 Apr 27. pii: 201801242.
产品手册
关联产品
-
Propofol
A widely used general anesthetic to induce and maintain anesthesia; influences ligand-gated channels.
-
Paprotrain
Paprotrain inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM.
-
Kinesore
Kinesore is a small molecule activator of kinesin-1 that inhibits KLC2-SKIP interaction with IC50 of 101 uM, Ki of 49 uM.
