• 咨询热线
    客服服务热线 13671568941/15317326293
  • 在线咨询
  • 微信客服
    微信客服
  • 公众号
    扫码关注公众号

Kif15-IN-1

CAS No. 672926-32-8

Kif15-IN-1 ( KIF15-IN-1; KIF15IN-1; KIF15-IN1; KIF15IN1; KIF15 IN 1 )

产品货号. M15567 CAS No. 672926-32-8

Kif15-IN-1 is a potent, selective inhibitor of KIF15 motility, can act synergistically with Eg5 inhibitors to impair cancer cell proliferation.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥2811 有现货
50MG ¥12069 有现货
100MG ¥16119 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Kif15-IN-1
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Kif15-IN-1 is a potent, selective inhibitor of KIF15 motility, can act synergistically with Eg5 inhibitors to impair cancer cell proliferation.
  • 产品描述
    Kif15-IN-1 is a potent, selective inhibitor of KIF15 motility, can act synergistically with Eg5 inhibitors to impair cancer cell proliferation.
  • 同义词
    KIF15-IN-1; KIF15IN-1; KIF15-IN1; KIF15IN1; KIF15 IN 1
  • 通路
    Cytoskeleton/Cell Adhesion Molecules
  • 靶点
    Kinesin
  • 受体
    Kinesin
  • 研究领域
    Cancer
  • 适应症
    ——

化学信息

  • CAS Number
    672926-32-8
  • 分子量
    430.48
  • 分子式
    C20H22N4O5S
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO : ≥ 100 mg/mL 232.30 mM; H2O : < 0.1 mg/mL
  • SMILES
    O=C(C1=C(C)N=C(NC([C@@H](N2C(NC3=C(C=CC=C3)C2=O)=O)C(C)C)=O)S1)OCC
  • 化学全称
    ethyl (S)-2-(2-(2,4-dioxo-1,4-dihydroquinazolin-3(2H)-yl)-3-methylbutanamido)-4-methylthiazole-5-carboxylate

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Preparation of quinazolinediones as Kif15 kinesin inhibitors for treating cellular proliferative disorders. Pat. Appl. Publ. (2004), US 20040053948 A1 20040318.
2. Milic B, et al. Proc Natl Acad Sci U S A. 2018 Apr 27. pii: 201801242.
产品手册
关联产品
  • CK-0106023

    A potent, specific, allosteric inhibitor of KSP motor domain ATPase with Ki of 12 nM.

  • PVZB-1194

    PVZB-1194 is a bis(hetero)aryl derivative that inhibits kinesin spindle protein (KSP) ATPase witn IC50 of 0.12 uM.

  • TCS-OX2-29

    TCS-OX2-29 is a potent and selective OX2 receptor antagonist (IC50: 40 nM). It displays >250-fold selectivity for OX2 over OX1.