Iloperidone
CAS No. 133454-47-4
Iloperidone ( HP-873 )
产品货号. M11335 CAS No. 133454-47-4
An atypical antipsychotic that exhibits high affinity to serotonin 5HT2A (Ki =5.6 nM), dopamine D2 (Ki=6.3 nM) and D3 (Ki=7.1 nM) and noradrenaline α1 receptors (Ki=0.36 nM).
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥267 | 有现货 |
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10MG | ¥405 | 有现货 |
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25MG | ¥770 | 有现货 |
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50MG | ¥1337 | 有现货 |
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100MG | ¥1985 | 有现货 |
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200MG | ¥2940 | 有现货 |
|
500MG | ¥4763 | 有现货 |
|
1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Iloperidone
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述An atypical antipsychotic that exhibits high affinity to serotonin 5HT2A (Ki =5.6 nM), dopamine D2 (Ki=6.3 nM) and D3 (Ki=7.1 nM) and noradrenaline α1 receptors (Ki=0.36 nM).
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产品描述An atypical antipsychotic that exhibits high affinity to serotonin 5HT2A (Ki =5.6 nM), dopamine D2 (Ki=6.3 nM) and D3 (Ki=7.1 nM) and noradrenaline α1 receptors (Ki=0.36 nM), moderate affinity for D4 (25 nM), 5HT6 (43 nM), 5HT7 (22 nM), and low affinity for 5HT1A (168 nM), D1 and histamine H1 receptors; is used for the treatment of schizophrenia.Schizophrenia Approved
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同义词HP-873
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通路Endocrinology/Hormones
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靶点5-HT Receptor
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受体Dopamine;α-adrenergicreceptor
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研究领域Neurological Disease
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适应症Schizophrenia
化学信息
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CAS Number133454-47-4
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分子量426.48
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分子式C24H27FN2O4
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纯度>98% (HPLC)
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溶解度10 mM in DMSO
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SMILESCC(C1=CC=C(OCCCN2CCC(C3=NOC4=CC(F)=CC=C34)CC2)C(OC)=C1)=O
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化学全称Ethanone, 1-[4-[3-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]propoxy]-3-methoxyphenyl]-
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Barr AM, et al. Neuropharmacology. 2006 Sep;51(3):457-65.
2. Szewczak MR, et al. J Pharmacol Exp Ther. 1995 Sep;274(3):1404-13.
3. Sainati SM, et al. J Clin Pharmacol. 1995 Jul;35(7):713-20.
2. Szewczak MR, et al. J Pharmacol Exp Ther. 1995 Sep;274(3):1404-13.
3. Sainati SM, et al. J Clin Pharmacol. 1995 Jul;35(7):713-20.
产品手册
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