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Iloperidone

CAS No. 133454-47-4

Iloperidone ( HP-873 )

产品货号. M11335 CAS No. 133454-47-4

An atypical antipsychotic that exhibits high affinity to serotonin 5HT2A (Ki =5.6 nM), dopamine D2 (Ki=6.3 nM) and D3 (Ki=7.1 nM) and noradrenaline α1 receptors (Ki=0.36 nM).

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥267 有现货
10MG ¥405 有现货
25MG ¥770 有现货
50MG ¥1337 有现货
100MG ¥1985 有现货
200MG ¥2940 有现货
500MG ¥4763 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Iloperidone
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    An atypical antipsychotic that exhibits high affinity to serotonin 5HT2A (Ki =5.6 nM), dopamine D2 (Ki=6.3 nM) and D3 (Ki=7.1 nM) and noradrenaline α1 receptors (Ki=0.36 nM).
  • 产品描述
    An atypical antipsychotic that exhibits high affinity to serotonin 5HT2A (Ki =5.6 nM), dopamine D2 (Ki=6.3 nM) and D3 (Ki=7.1 nM) and noradrenaline α1 receptors (Ki=0.36 nM), moderate affinity for D4 (25 nM), 5HT6 (43 nM), 5HT7 (22 nM), and low affinity for 5HT1A (168 nM), D1 and histamine H1 receptors; is used for the treatment of schizophrenia.Schizophrenia Approved
  • 同义词
    HP-873
  • 通路
    Endocrinology/Hormones
  • 靶点
    5-HT Receptor
  • 受体
    Dopamine;α-adrenergicreceptor
  • 研究领域
    Neurological Disease
  • 适应症
    Schizophrenia

化学信息

  • CAS Number
    133454-47-4
  • 分子量
    426.48
  • 分子式
    C24H27FN2O4
  • 纯度
    >98% (HPLC)
  • 溶解度
    10 mM in DMSO
  • SMILES
    CC(C1=CC=C(OCCCN2CCC(C3=NOC4=CC(F)=CC=C34)CC2)C(OC)=C1)=O
  • 化学全称
    Ethanone, 1-[4-[3-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]propoxy]-3-methoxyphenyl]-

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Barr AM, et al. Neuropharmacology. 2006 Sep;51(3):457-65.
2. Szewczak MR, et al. J Pharmacol Exp Ther. 1995 Sep;274(3):1404-13.
3. Sainati SM, et al. J Clin Pharmacol. 1995 Jul;35(7):713-20.
产品手册
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