IDH1-IN-1 ( Mutant IDH1-IN-1 )

产品货号. M11452 CAS No. 1355326-21-4

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

IDH1-IN-1
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Mutant IDH1-IN-1 is a potent mutant IDH1 R132H inhibitor with IC50 < 0.1 uM(A level in Patent).
产品描述

Mutant IDH1-IN-1 is a potent mutant IDH1 R132H inhibitor with IC50 < 0.1 uM(A level in Patent); more bioactivity information in Patent WO2012009678A1(Example 135).
同义词

Mutant IDH1-IN-1
通路

Metabolic Enzyme/Protease
靶点

Dehydrogenase
受体

mutant IDH1 R132H
研究领域

Cancer
适应症

——

CAS Number

1355326-21-4
分子量

498.59
分子式

C30H31FN4O2
纯度

>98%(HPLC)
溶解度

DMSO: 10 mM
SMILES

O=C(NC1CCCCC1)C(N(C(CN2C3=CC=CC=C3N=C2)=O)C4=CC=CC(F)=C4)C5=CC=CC=C5C
化学全称

2-(N-[2-(Benzimidazol-1-yl)acetyl]-3-fluoroanilino)-N-cyclohexyl-2-(2-methylphenyl)acetamide

1. Janeta Popovici-Muller, et al. Patent WO2012009678 A

计算器

产品手册

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