AVN944 ( AVN 944; AVN-944; AVN944; VX944; VX 944; VX-944. )

产品货号. M13910 CAS No. 297730-17-7

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

AVN944
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

AVN-944(VX-944) is a selective, noncompetitive inhibitor of the enzyme directed against human IMPDH with Ki of 6-10 nM for IMPDH1/IMPDH2.
产品描述

AVN-944(VX-944) is a selective, noncompetitive inhibitor of the enzyme directed against human IMPDH with Ki of 6-10 nM for IMPDH1/IMPDH2.
同义词

AVN 944; AVN-944; AVN944; VX944; VX 944; VX-944.
通路

Metabolic Enzyme/Protease
靶点

Dehydrogenase
受体

IMPDH
研究领域

Cancer
适应症

——

CAS Number

297730-17-7
分子量

477.51
分子式

C25H27N5O5
纯度

>98%(HPLC)
溶解度

DMSO: 58 mg/mL
SMILES

O=C(O[C@H](CC)CC#N)N[C@H](C1=CC=CC(NC(NC2=CC=C(C3=CN=CO3)C(OC)=C2)=O)=C1)C
化学全称

(R)-1-cyanobutan-2-yl ((S)-1-(3-(3-(3-methoxy-4-(oxazol-5-yl)phenyl)ureido)phenyl)ethyl)carbamate

1.Zimmermann AG, et al. Prog Nucleic Acid Res Mol Biol. 1998;61:181-209.

计算器

产品手册

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