HNHA ( —— )

产品货号. M27467 CAS No. 926908-04-5

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

HNHA
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

HNHA is an inhibitor of HDAC.
产品描述

HNHA is an inhibitor of HDAC.(In Vitro):Treatment of cells with HNHA could elicite histone hyperacetylation resulting in an up-regulation of cell cycle arrest, p21 transcription, and an inhibition of HT1080 cell invasion. HNHA was able to inhibit in-vitro HDAC enzyme activity as well as proliferation of human fibrosarcoma cells (HT1080). (In Vivo):Several HDAC inhibitors, including MS-27-275 and a hydroxyamide-based HDAC inhibitors such as SAHA have been investigated extensively and shown to inhibit tumor growth in vivo.
同义词

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通路

Cell Cycle/DNA Damage
靶点

HDAC
受体

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研究领域

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适应症

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1.Roch-Arveiller M, et al. Immunomodulatory effects of ornithine alpha-ketoglutarate in rats with burn injuries. Arch Surg. 1996 Jul;131(7):718-23.

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