Suprastat ( —— )

产品货号. M28984 CAS No. 90093-40-6

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Datasheet

HNMR

HPLC

MSDS

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产品名称

Suprastat
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Suprastat is an HDAC6 inhibitor used in silico simulations.
产品描述

Suprastat is an HDAC6 inhibitor used in silico simulations.(In Vitro):Suprastat demonstrates subnanomolar HDAC6 inhibitory potency and a hundred- to a thousand-fold HDAC6 selectivity over the other HDAC isoforms.(In Vivo):In vivo studies reveal that a combination of Suprastat and anti-PD1 immunotherapy enhances antitumor immune response, mediated by a decrease of protumoral M2 macrophages and increased infiltration of antitumor CD8+ effector and memory T-cells.
同义词

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通路

Cell Cycle/DNA Damage
靶点

HDAC
受体

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研究领域

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适应症

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1.Blunt J W , Copp B R , Keyzers R A , et al. Marine natural products[J]. Natural Product Reports, 2016, 33.

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