Goniothalamin

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Goniothalamin 是一种天然产物，已被证明可诱导多种癌细胞系凋亡，可诱导 RT4 细胞的细胞毒性和凋亡，通过诱导 caspase-3 诱导 HepG2 肝癌细胞凋亡，对 Chang 细胞系的敏感性较低。

Goniothalamin is a natural product that has been demonstrated to induce apoptosis in various cancer cell lines, can induce cytotoxicity and apoptosis on RT4 cells, induce apoptosis on HepG2 liver cancer cells via induction of caspase-3 with less sensitivity on the cell line of Chang cells. Goniothalamin has gastroprotective activity which is inhibited after pre-treatment with NEM (N-ethylmaleimide) and NSAID (non-steroidal anti-inflammatory drugs), highlighting the importance of sulfhydryl compounds and prostaglandins on Goniothalamin activity. Goniothalamin induces oxidative stresses and inhibits the expression of cell wall-associated proteins resulting in growth inhibition of Arabidopsis seedlings.(In Vitro):Goniothalamin induces apoptosis on HepG2 liver cancer cells via induction of caspase-3 with less sensitivity on the cell line of Chang cells. Goniothalamin induces oxidative stresses and inhibits the expression of cell wall-associated proteins resulting in growth inhibition of Arabidopsis seedlings.

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Endocrinology/Hormones

ATPase

ATPase

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17303-67-2

200.23

C13H12O2

>98% (HPLC)

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O=C1O[C@H](CC=C1)\C=C\c1ccccc1

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(-20℃)

With Ice Pack

≥ 2 years