Fenbufen

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

芬布芬是一种丙酸衍生物类非甾体抗炎药。

Fenbufen is a non-steroidal anti-inflammatory drug in the propionic acid derivatives class.(In Vitro):Fenbufen (100-500 μM) improves the viability of apoptotic THP-1 cells treated with 25 μM Nigericin (HY-127019).(In Vivo):Fenbufenmay (1200 mg/kg; feed) does not cause gastric ulceration whilst inducing a near maximal inhibition of prostaglandin release in rats.Fenbufenmay (1200 mg/kg; p.o.; diet; for 10 days) blocks the hypertrophy of the heart but not that of the skeletal muscles.

Fenbufen (100-500 μM) improves the viability of apoptotic THP-1 cells treated with 25 μM Nigericin (HY-127019).

Fenbufenmay (1200 mg/kg; feed) does not cause gastric ulceration whilst inducing a near maximal inhibition of prostaglandin release in rats.Fenbufenmay (1200 mg/kg; p.o.; diet; for 10 days) blocks the hypertrophy of the heart but not that of the skeletal muscles. Animal Model:Male hooded Lister ratsDosage:1200 mg/kg Administration:Oral administration, diet, for 10 days Result:Significantly reduced Clenbuterol (2mg/kg)-induced hypertrophy of the heart.

Fenbufen | Cinopal | Lederfen | CL-82204 | CL 82204 | CL82204

Endocrinology/Hormones

ATPase

ATP systhesis

Inflammation/Immunology

——

36330-85-5

254.28

C16H14O3

>98% (HPLC)

DMSO: 10 mM

O=C(O)CCC(C1=CC=C(C2=CC=CC=C2)C=C1)=O

4-([1,1'-biphenyl]-4-yl)-4-oxobutanoic acid

(-20℃)

With Ice Pack

≥ 2 years