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Giredestrant
CAS No. 1953133-47-5
Giredestrant ( GDC-9545 )
产品货号. M23885 CAS No. 1953133-47-5
Giredestrant potently competes with estradiol for binding and induces a conformational change within the ER ligand binding domain.?Giredestrant has anti-tumor activity.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥1887 | 有现货 |
|
| 5MG | ￥2341 | 有现货 |
|
| 10MG | ￥3750 | 有现货 |
|
| 25MG | ￥7063 | 有现货 |
|
| 50MG | ￥11259 | 有现货 |
|
| 100MG | ￥17658 | 有现货 |
|
| 200MG | ￥24057 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Giredestrant
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Giredestrant potently competes with estradiol for binding and induces a conformational change within the ER ligand binding domain.?Giredestrant has anti-tumor activity.
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产品描述Giredestrant potently competes with estradiol for binding and induces a conformational change within the ER ligand binding domain.?Giredestrant has anti-tumor activity.?Giredestrant, a non-steroidal ER ligand, is an orally active and selective estrogen receptor (ER) antagonist.?
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同义词GDC-9545
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通路Endocrinology/Hormones
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靶点Estrogen Receptor/ERR
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受体ER
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研究领域——
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适应症——
化学信息
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CAS Number1953133-47-5
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分子量522.6
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分子式C27H31F5N4O
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纯度>98% (HPLC)
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溶解度DMSO:100mg/mL (191.37 mM; Need ultrasonic)
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SMILESC[C@H](Cc1c2[nH]c3c1cccc3)N(CC(CO)(F)F)[C@@H]2c(c(F)cc(NC1CN(CCCF)C1)c1)c1F
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.C Metcalfe, et al. Abstract P5-04-07: GDC-9545: A novel ER antagonist and clinical candidate that combines desirable mechanistic and pre-clinical DMPK attributes
产品手册
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